Joel N. Meyer

Publications  

Papers Published

1. Meyer JN, Lord CA, Yang XY, Turner EA, Badireddy AR, Marinakos S, Chilkoti A, Wiesner MR, Auffan M, Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans, Aquatic Toxicol, vol. 100 (2010), pp. 140-150  [abs].
2. Leung MC-K, Goldstone JV, Boyd WA, Freedman JH, Meyer JN, Caenorhabditis elegans generates biologically relevant levels of genotoxic metabolites from aflatoxin B1 but not benzo[a]pyrene in vivo, Toxicological Sciences, vol. 118 (2010), pp. 444-453  [abs].
3. J.N. Meyer and B. Van Houten, Apparently normal DNA repair and transcript expression in the RB885 strain carrying an intronic deletion in the xpc-1 gene, Worm Breeder's Gazette, vol. 18 (2010), pp. 23 .
4. Boyd, W.A. and Lehmann, D.W. and Leung, M. C.-K. and Rodriguez, A. and Freedman, J.H. and Van Houten, B. and Meyer, J.N., Nucleotide excision repair is not detectably inducible, but is required for normal lifespan and growth, in genotoxin-stressed adult Caenorhabditis elegans., Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 683 (2010), pp. 57-67  [abs].
5. Hunter, SE and Jung, D and Di Giulio, RT and Meyer, JN, The QPCR assay for analysis of mitochondrial DNA damage, repair, and relative copy number, Methods, vol. 51 (2010), pp. 444-451  [abs].
6. Alexeyenko A, Wassenberg DM, Lobenhofer EK, Yen J, Sonnhammer ELL, Linney E, Meyer JN, Interactome-based analysis of the transcriptomic response to dioxin in developing zebrafish Danio rerio, PLoS ONE, vol. 5 (2010), pp. e10465  [abs].
7. Haugen, A.C. and Di Prospero, N.A. and Parker, J.S. and Fannin, R.D. and Chou, J. and Meyer, J.N. and Halweg, C. and Collins, J.B. and Durr, A. and Fischbeck, K. and Van Houten, B., Altered gene expression and DNA damage in peripheral blood cells from Friedreich's ataxia patients: cellular model of pathology., PLoS Genetics (2010)  [abs].
8. Boamah, E. and Brekman, A. and Tomasz, M. and Myeku, N. and Figueiredo-Pereira, M. and Hunter, S. and Meyer, J.N. and Bargonetti, J., DNA adducts of decarbamoyl mitomycin C efficiently kill cells with compromised p53 through proteasome-mediated degradation of Chk1., Chemical Research in Toxicology, vol. 23 (2010), pp. 1151-1162  [abs].
9. Meyer, J.N., QPCR: A tool for analysis of mitochondrial and nuclear DNA damage in ecotoxicology., Ecotoxicology, vol. 19 (2010), pp. 804-811  [abs].
10. Eischeid, A. C. and Meyer, J. N. and Linden, K. G., UV disinfection of adenoviruses: molecular indications of DNA damage efficiency, Appl Environ Microbiol, vol. 75 no. 1 (2009), pp. 23-8  [abs].
11. Jung, D. and Cho, Y. and Meyer, J. N. and Di Giulio, R. T., The long amplicon quantitative PCR for DNA damage assay as a sensitive method of assessing DNA damage in the environmental model, Atlantic killifish (Fundulus heteroclitus), Comp Biochem Physiol C Toxicol Pharmacol, vol. 149 no. 2 (2009), pp. 182-6  [abs].
12. Billiard, S. M. and Meyer, J. N. and Wassenberg, D. M. and Hodson, P. V. and Di Giulio, R. T., Nonadditive effects of PAHs on Early Vertebrate Development: mechanisms and implications for risk assessment, Toxicol Sci, vol. 105 no. 1 (2008), pp. 5-23  [abs].
13. Leung, M. C.-K. and Williams, P.L. and Benedetto, A. and Au, C. and Helmke, K.J. and Aschner, M. and Meyer, J.N., Caenorhabditis elegans: an Emerging Model in Biomedical and Environmental Toxicology, Toxicological Sciences, vol. 106 (2008), pp. 5-28  [abs].
14. Meyer, J. N. and Boyd, W. A. and Azzam, G. A. and Haugen, A. C. and Freedman, J. H. and Van Houten, B., Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans, Genome Biol, vol. 8 no. 5 (2007), pp. R70  [abs].
15. Chan, S. S. and Santos, J. H. and Meyer, J. N. and Mandavilli, B. S. and Cook, D. L., Jr. and McCash, C. L. and Kissling, G. E. and Nyska, A. and Foley, J. F. and van Houten, B. and Copeland, W. C. and Walker, V. E. and Witt, K. L. and Bishop, J. B., Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination, Environ Mol Mutagen, vol. 48 no. 3-4 (2007), pp. 190-200  [abs].
16. Burnett, K. G. and Bain, L. J. and Baldwin, W. S. and Callard, G. V. and Cohen, S. and Di Giulio, R. T. and Evans, D. H. and Gomez-Chiarri, M. and Hahn, M. E. and Hoover, C. A. and Karchner, S. I. and Katoh, F. and Maclatchy, D. L. and Marshall, W. S. and Meyer, J. N. and Nacci, D. E. and Oleksiak, M. F. and Rees, B. B. and Singer, T. D. and Stegeman, J. J. and Towle, D. W. and Van Veld, P. A. and Vogelbein, W. K. and Whitehead, A. and Winn, R. N. and Crawford, D. L., Fundulus as the Premier Teleost Model in Environmental Biology: Opportunities for New Insights Using Genomics, Comp Biochem Physiol Part D Genomics Proteomics, vol. 2 no. 4 (2007), pp. 257-286  [abs].
17. Wielgus, A. R. and Chignell, C. F. and Miller, D. S. and Van Houten, B. and Meyer, J. and Hu, D. N. and Roberts, J. E., Phototoxicity in Human Retinal Epithelial Cells Promoted by Hypericin, a Component of St. John's Wort, Photochem Photobiol (2006)  [abs].
18. Santos, J.H., Meyer, J.N., Mandavilli, B.S., and Van Houten, B., Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair inmammalian cells, in Methods in Molecular Biology: DNA repair protocols: Mammalian Systems, 2nd Edition, edited by Daryl Henderson, vol. 314 (2006), pp. 183-199, Humana Press Inc., Totawa, NJ, USA  [abs].
19. Santos, J.H., Meyer, J.N., and Van Houten, B., Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis, Human Molecular Genetics, vol. 15 (2006), pp. 1757-1768  [abs].
20. Meyer, J. N. and Volz, D. C. and Freedman, J. H. and Di Giulio, R. T., Differential display of hepatic mRNA from killifish (Fundulus heteroclitus) inhabiting a Superfund estuary, Aquat Toxicol, vol. 73 no. 4 (2005), pp. 327-41  [abs].
21. Timme-Laragy, A. R. and Meyer, J. N. and Waterland, R. A. and Di Giulio, R. T., Analysis of CpG methylation in the killifish CYP1A promoter, Comp Biochem Physiol C Toxicol Pharmacol, vol. 141 no. 4 (2005), pp. 406-11  [abs].
22. Santos, J. H. and Meyer, J. N. and Skorvaga, M. and Annab, L. A. and Van Houten, B., Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage, Aging Cell, vol. 3 no. 6 (2004), pp. 399-411  [abs].
23. Meyer, J. N. and Smith, J. D. and Winston, G. W. and Di Giulio, R. T., Antioxidant defenses in killifish (Fundulus heteroclitus) exposed to contaminated sediments and model prooxidants: short-term and heritable responses, Aquat Toxicol, vol. 65 no. 4 (2003), pp. 377-95  [abs].
24. Meyer, J. N. and Di Giuliuo, R. T., Heritable adaptation and fitness costs in killifish (Fundulus beteroclitus) inhabiting a polluted estuary, Ecological Applications, vol. 13 no. 2 (2003), pp. 490-503  [abs].
25. Meyer, J. N. and Wassenberg, D. M. and Karchner, S. I. and Hahn, M. E. and Di Giulio, R. T., Expression and inducibility of aryl hydrocarbon receptor pathway genes in wild-caught killifish (Fundulus heteroclitus) with different contaminant-exposure histories, Environmental Toxicology and Chemistry, vol. 22 no. 10 (2003), pp. 2337-2343  [abs].
26. Meyer, J. N. and Nacci, D. E. and Di Giulio, R. T., Cytochrome P4501A (CYP1A) in killifish (Fundulus heteroclitus): heritability of altered expression and relationship to survival in contaminated sediments, Toxicol Sci, vol. 68 no. 1 (2002), pp. 69-81  [abs].
27. Meyer, J. and Di Giulio, R., Patterns of heritability of decreased EROD activity and resistance to PCB 126-induced teratogenesis in laboratory-reared offspring of killifish (Fundulus heteroclitus) from a creosote-contaminated site in the Elizabeth River, VA, USA, Marine Environmental Research, vol. 54 no. 3-5 (2002), pp. 621-626  [abs].
28. Keller, J.M., Meyer, J.N., Mattie, M., Augspurger, T., Rau, M., Dong, J., and Levin, E., Assessment of immunotoxicology in wild populations: Review and recommendations, Reviews in Toxicology, vol. 3 (1999/2000), pp. 167-212 .

Papers Accepted

1. J.N. Meyer, Quantitative Analysis of DNA damage and repair in nuclear and mitochondrial DNA of animal cells using quantitative PCR, Methods in Molecular Biology (2011) .
2. J.N. Meyer, Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers, J Biol Chem (2011) .
3. J.N. Meyer, The mechanism of silver nanoparticle toxicity is dependent on dissolved silver and surface coating in Caenorhabditis elegans, Environ Sci & Technol (2011) .

Papers Submitted

1. J.N. Meyer, Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage, PLoS ONE (2011) .
2. J.N. Meyer, Mitochondrial DNA-dependent activation of protein kinase D1 (PKD1) by bleomycin induces apoptosis in A549 cells, American Journal of Physiology - Lung Cellular and Molecular Physiology (2011) .
3. Brar SS, Meyer JN, Bonini MG, Bortner C, Van Houten B, Martin WJ II, Mitochondrial DNA-dependent activation of Protein Kinase D1 (PKD1) by bleomycin induces apoptosis in A549 cells (2010) .
4. Furda A, Santos JH, Meyer JN, Van Houten B, Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. (2010) .

Book Chapters

1. J.N. Meyer, Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells, in DNA Repair Protocols, 3rd edition (2011) .
2. Kullman, S.W. and Mattingly, C, J. and Meyer, J.N. and Whitehead, A., Perspectives on Informatics in Toxicology., in A Textbook of Modern Toxicology, edited by Sons, John Wiley and (2010) .
3. Di Giulio RT and Meyer JN, Reactive oxygen species and oxidative stress, in The Toxicology of Fishes, edited by Di Giulio R.T. and Hinton D.E. (2008), pp. 273-324, Taylor and Francis .