Richard T Di Giulio

Publications  

Papers Published

1. Timme-Laragy, A.R., P.D. Noyes, D.R. Buhler, and R.T. Di Giulio, CYP1B1 knockdown does not alter synergistic developmental toxicity of polycyclic aromatic hydrocarbons in zebrafish (Danio rerio), Marine Environmental Research, vol. 66 no. 85-87 (2008) .
2. Matson, C.W., A.R. Timme-Laragy, and R.T. Di Giulio, Fluoranthene, but not benzo[a]pyrene, interacts with hypoxia resulting in pericardial effusion and lordosis in developing zebrafish, Chemosphere, vol. 74 (2008), pp. 149-154 .
3. Matson, C.W., B.W. Clark, M.J. Jenny, C.R. Fleming, M.E. Hahn, and R.T. Di Giulio, Development of the morpholino gene knockdown technique in Fundulus heteroclitus: a tool for studying molecular mechanisms in an established environmental model, Aquatic Toxicol, vol. 87 (2008), pp. 289-295 .
4. Larose, C., R. Canuel, M. Lucotte, P. Spear, and R.T. Di Giulio, Toxicological effects of methylmercury on walleye (Sander vitreus) and perch (Perca flavescens) from lakes of the boreal forest, Comparative Biochem & Physiol, vol. 147C (2008), pp. 139-149 .
5. Bohonowych, J.E.S., B. Zhao, A. Timme-Laragy, D. Jung, R.T. Di Giulio, and M.S. Denison, Newspapers and newspaper inks contain agonists for the AH receptor, Toxicological Sciences, vol. 102 (2008), pp. 278-290 .
6. Billiard, S.M., Meyer, J.N., Wassenberg, D.M., Hodson, P.V., and Di Giulio, R.T., Nonadditive effects of PAHs on early vertebrate development: mechanisms and implications for risk assessment, Toxicological Sciences, vol. 105 (2008), pp. 5-23 .
7. Augspurger, T.P., D.E. Tillitt, S.J. Bursian, S.D. Fitzgerald, D.E. Hinton, and R.T. Di Giulio, Embryotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin to the wood duck (Aix sponsa), Archives of Environmental Contamination and Toxicology, vol. 55 (2008), pp. 659-669 .
8. Augspurger, T.P. K.R. Echols, P.H. Peterman, T.W. May, C.E. Orazio, D.E. Tillitt, and R.T. Di Giulio, Accumulation of environmental contaminants in wood duck (Aix sponsa) eggs with emphasis on 2,3,7,,8-tetrachlordibenzo-p-dioxin equivalents, Archives of Environmental Contamination and Toxicology, vol. 55 (2008), pp. 670-682 .
9. Timme-Laragy, A.R., C.J. Cockman, C.W. Matson, and R.T. Di Giulio, Synergistic upregulation of AHR regulated genes in developmental toxicity of a polycyclic aromatic hydrocarbon mixture to zebrafish, Aquatic Toxicology (In press) .
10. Rau Embry, M., S.M. Billiard, and R.T. Di Giulio, Lack of p53 induction in fish cells by model chemotherapeutics, Oncogene, vol. 25 (2006), pp. 2004-2010 .
11. Billiard, S., A.R. Timme-Laragy, D.M. Wassenberg, C.Cockman, and R.T. Di Giulio, The role of the aryl hydrocarbon receptor pathway in mediating synergistic developmental toxicity of polycyclic aromatic hydrocarbons to zebrafish, Toxicological Sciences, vol. 92 (2006), pp. 526-536 .
12. Wassenberg, D., A. Nerlinger, L.Battle, and R.T. Di Giulio, Effects of the PAH-heterocycles, carbazole and dibenzothiophene, on invivo and invitro CYP1A activity and PAH-derived embryotoxicity, Environmental Toxicology and Chemistry, vol. 24 (2005), pp. 2526-2532 .
13. Timme-Laragy, A.R., J.N. Meyer, R.A. Waterland, and R.T. Di Giulio, Analysis of CpG methylation in the killifish CYP1A promoter, Comparative Biochemistry and Physiology, Part C, vol. 141 (2005), pp. 406-411 .
14. Meyer, J.N., D.C. Volz, J.H. Freedman, and R.T. Di Giulio, Differential display of hepatic mRNA from killifish (Fundulus heteroclitus) inhabiting a Superfund estuary, Aquatic Toxicology, vol. 73 (2005), pp. 327-341 .
15. Wassenberg, D.M., and R.T. Di Giulio, Synergistic embryotoxicity of polycyclic aromatic hydrocarbon aryl hydrocarbon receptor agonists with cytochrome P4501A inhibitors in Fundulus heteroclitus, Environmental Health Perspectives, vol. 112 (2004), pp. 1658-1664 .
16. Wassenberg, D.M., and R.T. Di Giulio, Teratogenesis in Fundulus heteroclitus embryos exposed to a creosote-contaminated sediment extract and CYP1A inhibitors, Marine Environmental Research, vol. 58 (2004), pp. 163-168 .
17. Bacanskas, L.R., J. Whitaker, and R.T. Di Giulio, Oxidative stress in two populations of killifish (Fundulus heteroclitus) with differing contaminant exposure histories, Marine Environmental Research, vol. 58 (2004), pp. 597-601 .
18. Rau, M.A., J. Whitaker, J.H. Freedman, and R.T. Di Giulio, Differential susceptibility of fish and rat liver cells to oxidative stress and cytotoxicity upon exposure to prooxidants, Comparative Biochemistry and Physiology, vol. 137C (2004), pp. 335-342 .
19. Meyer, J.N., and R.T. Di Giulio, Genetic adaptation and associated fitness tradeoffs in killifish (Fundulus heteroclitus) inhabiting a contaminated estuary, Ecological Applications, vol. 13 (2003), pp. 490-503 .
20. Meyer, J.N., D.M. Wassenberg, S.I. Karchner, M.E. Hahn, and R.T. Di Giulio, Expression and inducibility of aryl hydrocarbon receptor (AHR) pathway genes in wild-caught killifish (Fundulus heteroclitus) with different contaminant-exposure histories, Environmental Toxicology and Chemistry, vol. 22 (2003), pp. 2337-2343 .
21. Meyer, J.N., J.D. Smith, G.W. Winston, and R.T. Di Giulio, Antioxidant defenses in killifish (Fundulus heteroclitus) exposed to contaminated sediments and model prooxidants: short-term and heritable responses, Aquatic Toxicology, vol. 65 (2003), pp. 377-395 .
22. Meyer, J.N., D. Nacci, and R.T. Di Giulio, Cytochrome P4501A (CYP1A) in killifish (Fundulus heteroclitus): heritability of altered expression and relationship to survival in contaminated sediments, Toxicological Sciences, vol. 68 (2002), pp. 69-81 .
23. Meyer, J., and R. Di Giulio, Patterns of heritability of decreased EROD activity and resistance to PCB 126-induced teratogenesis in laboratory-reared offspring of killifish (Fundulus heteroclitus) from a creosote-contaminated site in the Elizabeth River, VA, USA., Marine Environmental Research, vol. 54 (2002), pp. 621-626 .
24. Wassenberg, D., E. Swails, and R. Di Giulio, Effects of combined exposures to benzo[a]pyrene and 3,3',4,4',5-pentachlorobiphenyl on Fundulus heteroclitus, Marine Environmental Research, vol. 54 (2002), pp. 279-283 .

Papers Accepted

1. Jung, D., Y. Cho, J.N. Meyer, and R.T. Di Giulio, The long amplicon quantitative PCR for DNA damage assay as a sensitive method of assessing DNA damage in the environmental model, Atlantic killifish (Fundulus heteroclitus), Comparative Biochem & Physiol, vol. in press (2008) [007] .
2. Timme-Laragy, A.R., L.A. Van Tiem, and R.T. Di Giulio, Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish, Toxicological Sciences, vol. accepted (2008) .
3. Battle, L.P., S. Zhu, K.L. Willett, and R.T. Di Giulio, Effect of the CYP1A inhibitor fluoranthene on the biotransformation of benzo[a]pyrene in two populations of Fundulus heteroclitus with different exposure histories, Aquatic Toxicol, vol. accepted (2008) .

Books Published

1. Di Giulio, R.T., and D.E. Hinton, The Toxicology of Fishes (2008), CRC Press, Taylor and Francis Group .
2. Genomic Approaches for Cross-Species Extrapolations in Toxicology, edited by Benson, W.H., and R.T. Di Giulio (2007), Taylor and Francis, New York .
3. The Toxicology of Fishes, edited by Di Giulio, R.T., and D.E. Hinton (In Press), Taylor and Francis, New York .
4. Interconnections between Human Health and Ecological Integrity, edited by Di Giulio, R.T., and W.H. Benson (2002), SETAC Press, Pensacola, FL. .
5. Reproductive and Developmental Effects of Contaminants in Oviparous Vertebrates, edited by Di Giulio, R.T., and D.E. Tillitt (1999), SETAC Press, Pensacola, FL .
6. Interconnections Between Human and Ecosystem Health, edited by Di Giulio, R.T., and E. Monosson (1996), Chapman and Hall, London .

Book Chapters

1. Di Giulio, R.T. and M.C. Newman, Ecotoxicology, in Casarett and Doull's Toxicology. The Basic Science of Poisons, edited by Klaassen, C.D. (2008), McGraw Hill .
2. Rotchell, J.M., D.E. Hinton, M.R. Miller, R.T. Di Giulio, and G.K. Ostrander, Chemical carcinogenesis in fishes, in The Toxicology of Fishes, edited by Di Giulio and Hinton (2008), pp. 531-598, CRC .
3. Di Giulio, R.T. and J.N. Meyer, Reactive oxygen species and oxidative stress, in The Toxicology of Fishes, edited by Di Giulio, R.T., and D.E. Hinton (2008), pp. 273-324, CRC .
4. R.T. Di Giulio and M.C. Newman, Ecotoxicology, in Klaassen, C.D., ed. Casarett and Doull's Toxicology. The Basic Science of Poisons, 6th edition (In Press), McGraw-Hill .
5. R.T. Di Giulio and J.N. Meyer, Reactive oxygen species and oxidative stress, in Di Giulio, R.T., andD.E. Hinton, eds. The Toxicology of Fishes (In Press), Taylor and Francis, New York .
6. Rotchell, J.M., D.E. Hinton, M.R. Miller, R.T. Di Giulio and G.K. Ostrander, Chemical carcinogenesis in fishes, in Di Giulio, R.T., and D.E. Hinton, eds. The Toxicology of Fishes (In Press), Taylor and Francis, New York .
7. Nacci, D., L. Coiro, D.M. Wassenberg, and R.T. Di Giulio, A non-destructive technique to measure cytochrome P4501A enzyme activity in living embryos of the estuarine fish Fundulus heteroclitus, in Techniques in Aquatic Toxicology, edited by Ostrander, G.K., vol. 2 (2005), pp. 209-226, CRC Press, Boca Raton, FL. .
8. Schlenk, D., and R.T. Di Giulio, Biochemical responses as indicators of aquatic ecosystem health, in Biological Indicators of Aquatic Ecosystem Stress, edited by S.M. Adams (2002), pp. 13-422, American Fisheries Society, Bethesda, MD. .