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Richard T. Di Giulio

Richard T. Di Giulio

Publications  

Papers Published

  1. Timme-Laragy, A.R., C.J. Cockman, C.W. Matson, and R.T. Di Giulio, Synergistic upregulation of AHR regulated genes in developmental toxicity of a polycyclic aromatic hydrocarbon mixture to zebrafish, Aquatic Toxicology (In press) .
  2. Rau Embry, M., S.M. Billiard, and R.T. Di Giulio, Lack of p53 induction in fish cells by model chemotherapeutics, Oncogene, vol. 25 (2006), pp. 2004-2010 .
  3. Billiard, S., A.R. Timme-Laragy, D.M. Wassenberg, C.Cockman, and R.T. Di Giulio, The role of the aryl hydrocarbon receptor pathway in mediating synergistic developmental toxicity of polycyclic aromatic hydrocarbons to zebrafish, Toxicological Sciences, vol. 92 (2006), pp. 526-536 .
  4. Wassenberg, D., A. Nerlinger, L.Battle, and R.T. Di Giulio, Effects of the PAH-heterocycles, carbazole and dibenzothiophene, on invivo and invitro CYP1A activity and PAH-derived embryotoxicity, Environmental Toxicology and Chemistry, vol. 24 (2005), pp. 2526-2532 .
  5. Timme-Laragy, A.R., J.N. Meyer, R.A. Waterland, and R.T. Di Giulio, Analysis of CpG methylation in the killifish CYP1A promoter, Comparative Biochemistry and Physiology, Part C, vol. 141 (2005), pp. 406-411 .
  6. Meyer, J.N., D.C. Volz, J.H. Freedman, and R.T. Di Giulio, Differential display of hepatic mRNA from killifish (Fundulus heteroclitus) inhabiting a Superfund estuary, Aquatic Toxicology, vol. 73 (2005), pp. 327-341 .
  7. Wassenberg, D.M., and R.T. Di Giulio, Synergistic embryotoxicity of polycyclic aromatic hydrocarbon aryl hydrocarbon receptor agonists with cytochrome P4501A inhibitors in Fundulus heteroclitus, Environmental Health Perspectives, vol. 112 (2004), pp. 1658-1664 .
  8. Wassenberg, D.M., and R.T. Di Giulio, Teratogenesis in Fundulus heteroclitus embryos exposed to a creosote-contaminated sediment extract and CYP1A inhibitors, Marine Environmental Research, vol. 58 (2004), pp. 163-168 .
  9. Bacanskas, L.R., J. Whitaker, and R.T. Di Giulio, Oxidative stress in two populations of killifish (Fundulus heteroclitus) with differing contaminant exposure histories, Marine Environmental Research, vol. 58 (2004), pp. 597-601 .
  10. Rau, M.A., J. Whitaker, J.H. Freedman, and R.T. Di Giulio, Differential susceptibility of fish and rat liver cells to oxidative stress and cytotoxicity upon exposure to prooxidants, Comparative Biochemistry and Physiology, vol. 137C (2004), pp. 335-342 .
  11. Meyer, J.N., and R.T. Di Giulio, Genetic adaptation and associated fitness tradeoffs in killifish (Fundulus heteroclitus) inhabiting a contaminated estuary, Ecological Applications, vol. 13 (2003), pp. 490-503 .
  12. Meyer, J.N., D.M. Wassenberg, S.I. Karchner, M.E. Hahn, and R.T. Di Giulio, Expression and inducibility of aryl hydrocarbon receptor (AHR) pathway genes in wild-caught killifish (Fundulus heteroclitus) with different contaminant-exposure histories, Environmental Toxicology and Chemistry, vol. 22 (2003), pp. 2337-2343 .
  13. Meyer, J.N., J.D. Smith, G.W. Winston, and R.T. Di Giulio, Antioxidant defenses in killifish (Fundulus heteroclitus) exposed to contaminated sediments and model prooxidants: short-term and heritable responses, Aquatic Toxicology, vol. 65 (2003), pp. 377-395 .
  14. Meyer, J.N., D. Nacci, and R.T. Di Giulio, Cytochrome P4501A (CYP1A) in killifish (Fundulus heteroclitus): heritability of altered expression and relationship to survival in contaminated sediments, Toxicological Sciences, vol. 68 (2002), pp. 69-81 .
  15. Meyer, J., and R. Di Giulio, Patterns of heritability of decreased EROD activity and resistance to PCB 126-induced teratogenesis in laboratory-reared offspring of killifish (Fundulus heteroclitus) from a creosote-contaminated site in the Elizabeth River, VA, USA., Marine Environmental Research, vol. 54 (2002), pp. 621-626 .
  16. Wassenberg, D., E. Swails, and R. Di Giulio, Effects of combined exposures to benzo[a]pyrene and 3,3',4,4',5-pentachlorobiphenyl on Fundulus heteroclitus, Marine Environmental Research, vol. 54 (2002), pp. 279-283 .

Books

  1. Genomic Approaches for Cross-Species Extrapolations in Toxicology, edited by Benson, W.H., and R.T. Di Giulio (2007), Taylor and Francis, New York .
  2. The Toxicology of Fishes, edited by Di Giulio, R.T., and D.E. Hinton (In Press), Taylor and Francis, New York .
  3. Interconnections between Human Health and Ecological Integrity, edited by Di Giulio, R.T., and W.H. Benson (2002), SETAC Press, Pensacola, FL. .
  4. Reproductive and Developmental Effects of Contaminants in Oviparous Vertebrates, edited by Di Giulio, R.T., and D.E. Tillitt (1999), SETAC Press, Pensacola, FL .
  5. Interconnections Between Human and Ecosystem Health, edited by Di Giulio, R.T., and E. Monosson (1996), Chapman and Hall, London .

Book Chapters

  1. R.T. Di Giulio and M.C. Newman, Ecotoxicology, in Klaassen, C.D., ed. Casarett and Doull's Toxicology. The Basic Science of Poisons, 6th edition (In Press), McGraw-Hill .
  2. R.T. Di Giulio and J.N. Meyer, Reactive oxygen species and oxidative stress, in Di Giulio, R.T., andD.E. Hinton, eds. The Toxicology of Fishes (In Press), Taylor and Francis, New York .
  3. Rotchell, J.M., D.E. Hinton, M.R. Miller, R.T. Di Giulio and G.K. Ostrander, Chemical carcinogenesis in fishes, in Di Giulio, R.T., and D.E. Hinton, eds. The Toxicology of Fishes (In Press), Taylor and Francis, New York .
  4. Nacci, D., L. Coiro, D.M. Wassenberg, and R.T. Di Giulio, A non-destructive technique to measure cytochrome P4501A enzyme activity in living embryos of the estuarine fish Fundulus heteroclitus, in Techniques in Aquatic Toxicology, edited by Ostrander, G.K., vol. 2 (2005), pp. 209-226, CRC Press, Boca Raton, FL. .
  5. Schlenk, D., and R.T. Di Giulio, Biochemical responses as indicators of aquatic ecosystem health, in Biological Indicators of Aquatic Ecosystem Stress, edited by S.M. Adams (2002), pp. 13-422, American Fisheries Society, Bethesda, MD. .
    



 

Contact Di Giulio at:

A346B LSRC
Box 90328
Durham, NC 27708
919-613-8024
fax: 919-668-1799
richd@duke.edu