Publications [#155139] of Celia J Bonaventura

Working Papers

1. C.J. Bonaventura, R. Henkens, A.I. Alayash and A.L. Crumbliss, Heme Access Determines the Propensities of Human and Clam Hbs for Nitrite-Induced Oxidation, JBC (Spring, 2009)
   (last updated on 2009/01/15)

   Author's Comments:
   This is one of three papers I will publish in 2009 that show the importance of steric factors and conformational fluctuations in the control of hemoglobin function.

   Abstract:
   Clam Hbs provide useful information of how nitrite can regulate blood pressure. Oxygen was found to play a critical role in "clamming up" the active site of a nitrite-resistant clam Hb.

   Keywords:
   hemoglobin • oxidative damage • nitrosative damage