Publications [#278763] of Dennis A. Clements

Papers Published

1. Clements, DA; Weigle, KA; Gilbert, GL, A case-control study examining risk factors for invasive Haemophilus influenzae type b disease in Victoria, Australia 1988-90., Journal of Paediatrics and Child Health, vol. 31 no. 6 (December, 1995), pp. 513-518, ISSN 1034-4810 [8924302], [doi]
   (last updated on 2023/06/01)

   Abstract:
   OBJECTIVE: To determine whether day-care attendance was a risk factor for Haemophilus influenzae type b (Hib) disease, particularly for epiglottitis. METHODOLOGY: A case-control analysis of risk factors for invasive Hib disease was performed in Victoria, Australia between February 1988 and February 1990 prior to the introduction of immunization for Hib. A total of 210 cases and 367 day surgery hospital controls were enrolled prospectively. Data were collected by questionnaire at the time of admission. RESULTS: Logistic regression analysis showed that risk factors for meningitis were day-care attendance, household crowding and recent illness in a sibling. Risk factors for epiglottitis were day-care attendance and mother's birthplace in Australia or New Zealand. CONCLUSIONS: This study confirms that day-care attendance is a risk factor for Hib epiglottitis as well as meningitis. In addition, the mother's birthplace in Australia or New Zealand is a risk factor for epiglottitis in these data. The reason for this latter observation is unclear.

   Keywords:
   Case-Control Studies • Child Day Care Centers* • Child, Preschool • Female • Haemophilus Infections • Haemophilus influenzae* • Humans • Infant • Infant, Newborn • Logistic Models • Male • Population Surveillance • Prospective Studies • Questionnaires • Risk Factors • Victoria • epidemiology • etiology*