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Grant Name: Exceptional Survival in Danish and Italian Families [web]
Grant Number: U01 AG023712
Funding Agency: NIA (funded for 5 years)
PIs: James W. Vaupel
Investigators/Advisors: Kaare Christensen, Anatoli Yashin, Jutta Gampe
Effective Dates: 2004/09-2009/05
Approximate Amount/Year: $500,000
Approximate Total: $2,600,000
Description: (This project description is based on
text as submitted in the original grant but updated to
reflect the scope and/or findings of the funded
research project.)
This 5-year project is part of
the: Long Life Family Study. In particular, we
plan to gather questionnaire and physiological
data on 300 Danish families in which there are
pairs of living nonagenarian and centenarian sibs
and living brothers, sisters, and spouses and
children. We are expecting that each family will
give the research team approximately seven family
members. The spouses will be in a control group of
family members. We will gather information on the
lifespans of the sibs' parents and validate all
ages by examining birth certificates and, when
appropriate, marriage certificates and death
certificates. In this research project, we will
collaborate with other Exceptional Survival in Families (ESF) Study Centers at (see
http://www.biostat.wustl.edu/llfs/ for full
information and project descriptions): University
of Pittsburgh, Washington University, Boston
University, Columbia University, and the NIA to
develop appropriate questionnaires and survey
procedures. Our plan is to develop powerful,
appropriate models and methods of
statistical/demographic analysis to study the data
in collaboration with other ESF Study Centers.
Notes: 1) This grant was funded only for Danish
Families. Italian
families are not included.
2) The grant application was submitted in response
to a NIA solicitation
having the title, “The NIA Multicenter Study of
Exceptional Survival in
Families,” and solicitation number, AG-03-004.
CRISP Thesaurus Terms: centenarian human (100+),
family, human population study, human very old age
(85+), longevity cooperative study, human
mortality, long term survivor, parent, physiology,
sibling, Scandinavian country, blood chemistry,
clinical research, death certificate, human
subject, questionnaire.