Publications [#365143] of Jenny Tung

Papers Published

1. Vilgalys, TP; Fogel, AS; Anderson, JA; Mututua, RS; Warutere, JK; Siodi, IL; Kim, SY; Voyles, TN; Robinson, JA; Wall, JD; Archie, EA; Alberts, SC; Tung, J, Selection against admixture and gene regulatory divergence in a long-term primate field study., Science (New York, N.Y.), vol. 377 no. 6606 (August, 2022), pp. 635-641 [doi]
   (last updated on 2024/04/24)

   Abstract:
   Genetic admixture is central to primate evolution. We combined 50 years of field observations of immigration and group demography with genomic data from ~9 generations of hybrid baboons to investigate the consequences of admixture in the wild. Despite no obvious fitness costs to hybrids, we found signatures of selection against admixture similar to those described for archaic hominins. These patterns were concentrated near genes where ancestry is strongly associated with gene expression. Our analyses also show that introgression is partially predictable across the genome. This study demonstrates the value of integrating genomic and field data for revealing how "genomic signatures of selection" (e.g., reduced introgression in low-recombination regions) manifest in nature; moreover, it underscores the importance of other primates as living models for human evolution.