Kenneth D. Poss, Professor  

Kenneth D. Poss

Modeling disease in zebrafish
Genetic approaches to organ regeneration
Cardiac regeneration
Appendage regeneration
Developmental biology

Ph.D., Massachusetts Institute of Technology, 1998

Office Location: 307 Research Drive, Nanaline Bldg Room 466 A, Durham, NC 27710
Office Phone: (919) 681-8457
Email Address:
Web Page:
Additional Web Page:

Representative Publications   (More Publications)   (search)

  1. Kikuchi, K; Holdway, JE; Major, RJ; Blum, N; Dahn, RD; Begemann, G; Poss, KD, Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration., Dev Cell, vol. 20 no. 3 (March, 2011), pp. 397-404 [21397850], [doi]  [abs].
  2. Poss, KD, Advances in understanding tissue regenerative capacity and mechanisms in animals., Nature Reviews. Genetics, vol. 11 no. 10 (October, 2010), pp. 710-722 [20838411], [doi]  [abs].
  3. Kikuchi, K; Holdway, JE; Werdich, AA; Anderson, RM; Fang, Y; Egnaczyk, GF; Evans, T; Macrae, CA; Stainier, DYR; Poss, KD, Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes., Nature, vol. 464 no. 7288 (March, 2010), pp. 601-605 [20336144], [doi]  [abs].
  4. Yin, VP; Thomson, JM; Thummel, R; Hyde, DR; Hammond, SM; Poss, KD, Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish., Genes & Development, vol. 22 no. 6 (March, 2008), pp. 728-733 [18347091], [doi]  [abs].
  5. Wills, AA; Holdway, JE; Major, RJ; Poss, KD, Regulated addition of new myocardial and epicardial cells fosters homeostatic cardiac growth and maintenance in adult zebrafish., Development (Cambridge, England), vol. 135 no. 1 (January, 2008), pp. 183-192 [18045840], [doi]  [abs].
  6. Poss, KD, Getting to the heart of regeneration in zebrafish., Seminars in Cell & Developmental Biology, vol. 18 no. 1 (February, 2007), pp. 36-45 [17178459], [doi]  [abs].
  7. Lepilina, A; Coon, AN; Kikuchi, K; Holdway, JE; Roberts, RW; Burns, CG; Poss, KD, A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration., Cell, vol. 127 no. 3 (November, 2006), pp. 607-619 [17081981], [doi]  [abs].
  8. Lee, Y; Grill, S; Sanchez, A; Murphy-Ryan, M; Poss, KD, Fgf signaling instructs position-dependent growth rate during zebrafish fin regeneration., Development (Cambridge, England), vol. 132 no. 23 (December, 2005), pp. 5173-5183 [16251209], [doi]  [abs].