Publications [#331530] of Mohamed A. Noor


Papers Published

  1. Ballinger, MA; Noor, MAF, Are Lethal Alleles Too Abundant in Humans?, Trends in Genetics (December, 2017) [doi] .
    (last updated on 2018/03/21)

    Across species, many individuals carry one or more recessive lethal alleles, posing an evolutionary conundrum for their persistence. Using a population genomic approach, Amorim et al. studied the abundance of lethal disease-causing mutations in humans and found that, while appearing more common than expected, most may nonetheless persist at frequencies predicted by mutation-selection balance.