Publications [#331530] of Mohamed A. Noor

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Papers Published

  1. Ballinger, MA; Noor, MAF, Are Lethal Alleles Too Abundant in Humans?, Trends in Genetics : Tig, vol. 34 no. 2 (February, 2018), pp. 87-89 [doi] .
    (last updated on 2018/12/15)

    Abstract:
    Across species, many individuals carry one or more recessive lethal alleles, posing an evolutionary conundrum for their persistence. Using a population genomic approach, Amorim et al. studied the abundance of lethal disease-causing mutations in humans and found that, while appearing more common than expected, most may nonetheless persist at frequencies predicted by mutation-selection balance.