Publications [#228071] of Philip N. Benfey
search PubMed.Papers Published
- Liberman, LM; Sozzani, R; Benfey, PN, Integrative systems biology: an attempt to describe a simple weed.,
Current Opinion in Plant Biology, vol. 15 no. 2
(April, 2012),
pp. 162-167 [22277598], [doi] .
(last updated on 2023/10/03)Abstract:
Genome-scale studies hold great promise for revealing novel plant biology. Because of the complexity of these techniques, numerous considerations need to be made before embarking on a study. Here we focus on the Arabidopsis model system because of the wealth of available genome-scale data. Many approaches are available that provide genome-scale information regarding the state of a given organism (e.g. genomics, epigenomics, transcriptomics, proteomics, metabolomics interactomics, ionomics, phenomics, etc.). Integration of all of these types of data will be necessary for a comprehensive description of Arabidopsis. In this review we propose that 'triangulation' among transcriptomics, proteomics and metabolomics is a meaningful approach for beginning this integrative analysis and uncovering a systems level perspective of Arabidopsis biology.