Publications [#229216] of Thomas Mitchell-Olds

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Papers Published

  1. Schranz, ME; Lysak, MA; Mitchell-Olds, T, The ABC's of comparative genomics in the Brassicaceae: building blocks of crucifer genomes., Trends in Plant Science, vol. 11 no. 11 (November, 2006), pp. 535-542 [17029932], [doi] .
    (last updated on 2019/07/18)

    Abstract:
    In this review we summarize recent advances in our understanding of phylogenetics, polyploidization and comparative genomics in the family Brassicaceae. These findings pave the way for a unified comparative genomic framework. We integrate several of these findings into a simple system of 24 conserved chromosomal blocks (labeled A-X). The naming, order, orientation and color-coding of these blocks are based on their positions in a proposed ancestral karyotype (n=8), rather than by their position in the reduced genome of Arabidopsis thaliana (n=5). We show how these crucifer building blocks can be rearranged to model the genome structures of A. thaliana, Arabidopsis lyrata, Capsella rubella and Brassica rapa. A framework for comparison between species is timely because several crucifer genome-sequencing projects are underway.