Publications [#262531] of Tuan Vo-Dinh

Papers Published

1. Vo-Dinh, T; Fales, AM; Griffin, GD; Khoury, CG; Liu, Y; Ngo, H; Norton, SJ; Register, JK; Wang, H-N; Yuan, H, Plasmonic nanoprobes: from chemical sensing to medical diagnostics and therapy., Nanoscale, vol. 5 no. 21 (November, 2013), pp. 10127-10140 [24056945], [doi]
   (last updated on 2024/04/24)

   Abstract:
   This article provides an overview of the development and applications of plasmonics-active nanoprobes in our laboratory for chemical sensing, medical diagnostics and therapy. Molecular Sentinel nanoprobes provide a unique tool for DNA/RNA biomarker detection both in a homogeneous solution or on a chip platform for medical diagnostics. The possibility of combining spectral selectivity and high sensitivity of the surface-enhanced Raman scattering (SERS) process with the inherent molecular specificity of nanoprobes provides an important multiplex diagnostic modality. Gold nanostars can provide an excellent multi-modality platform, combining two-photon luminescence with photothermal therapy as well as Raman imaging with photodynamic therapy. Several examples of optical detection using SERS and photonics-based treatments are presented to illustrate the usefulness and potential of the plasmonic nanoprobes for theranostics, which seamlessly combines diagnostics and therapy.