Publications [#262959] of Tuan Vo-Dinh

Papers Published

1. Martin, ME; Wabuyele, M; Panjehpour, M; Overholt, B; DeNovo, R; Kennel, S; Cunningham, G; Vo-Dinh, T, An AOTF-based dual-modality hyperspectral imaging system (DMHSI) capable of simultaneous fluorescence and reflectance imaging., Medical engineering & physics, vol. 28 no. 2 (March, 2006), pp. 149-155, ISSN 1350-4533 [15955718], [doi]
   (last updated on 2024/04/24)

   Abstract:
   An acousto-optic tunable filter (AOTF)-based system for dual-modality hyperspectral imaging (DMHSI) has been developed for use in characterization of normal and malignant mouse tissue. The system consists of a laser, endoscope, AOTF, and two cameras coupled with optics and electronics. Initial results show that the system can delineate normal and malignant mouse tissues real-time. The analysis shows that malignant tissues consistently exhibit less fluorescent intensity in the wavelength band from 440 to 540 nm with a peak intensity of around 490 nm. The analysis also shows key spectroscopic differences between normal and malignant tissues. Further, these results are compared to real-time spectroscopic data and show good correlation.

   Keywords:
   Fluorescence;Acoustooptical devices;Optical filters;Tissue;Spectroscopic analysis;Correlation methods;Biomedical engineering;