Publications [#263028] of Tuan Vo-Dinh

Papers Published

1. Sepaniak, MJ; Vo Dinh, T, Fibre-optic-based fluoroimmunosensors, Philos. Trans. R. Soc. A, Phys. Sci. Eng. (UK), vol. 333 no. 1628 (1990), pp. 85-92
   (last updated on 2024/04/23)

   Abstract:
   Remote sensing of chemicals can be performed using fibre optic chemical sensors that use immunochemical reagent phases. Exploiting the specificity of antibody-antigen interactions and the sensitivity of laser-excited fluorimetry, highly selective measurement of ultra-trace levels of chemicals can be performed remotely and in situ via fluoroimmunoassay techniques. In this work, heterogeneous assay protocols using immunobeads are implemented. A passive sensor that samples the analyte by diffusion through a permeable membrane and is capable of a single analysis is described and used for the measurement of a naturally fluorescent compound. Subsequently, a regenerable sensor that can perform assay procedures in a repetitive fashion is described and characterized. The versatility of this sensor for performing remote measurements using a variety of established fluoroimmunoassay methodologies is discussed

   Keywords:
   fibre optic sensors;fluorescence;spectrochemical analysis;