Barbara R. Shaw
Office: 1105 French Family Science Ctr, Box 90346, Chemistry Department, Durham, NC 2770
Phone: +1 919 451 9197
E-mail: 
Research Interests
Our laboratory studies the chemical reactivity of DNA and synthesizes modified nucleic acids as potential antitumor and antisense agents. We use biophysical, biochemical, and genetic techniques together with synthetic chemistry to understand pathways of mutation in DNA and to design novel nucleic acid analogues that might find use in the control of gene expression and signal transduction, in the treatment of tumors and cancer, and in antisense and gene therapy.
Publications
Most recent publications in PubMed