Alvin L. Crumbliss
Office: 2104 FFSC
Phone: (919) 660-1540
E-mail: 
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Research Interests
Dr. Crumbliss is a coordination chemist who studies the function, reactivity and mobility of transition metals in biological systems. A major emphasis in his lab currently is investigations related to the biochemistry of iron. Through application of kinetic, spectroscopic and electrochemical techniques the Crumbliss group is investigating low molecular weight iron carriers (siderophores and synthetic siderophore mimics) and high molecular weight iron carriers (mammalian and bacterial transferrin proteins) with respect to their ability to mobilize and deposit iron at specific sites in a biological system. The structure/function role of iron in heme proteins, such as the hemoglobins and myoglobins, is under investigation. Synthetic materials for metal-specific chelation designed using principles learned from biology are under investigation.
Publications
Most recent publications in PubMed