Publications [#233903] of Barbara R. Shaw

Journal Articles

  1. Sergueeva, ZA; Sergueev, DS; Shaw, BR, "Synthesis of dithymidine boranophosphates via stereospecific boronation of H-phosphonate diesters and assignment of their configuration", Tetrahedron LettersMarch,, 1999, 40(11), 2041-2044, Elsevier BV [Gateway.cgi], [doi].
    (last updated on 2024/04/24)

    Abstract:
    The absolute configurations of the two dithymidine boranophosphate isomers were established by chemical correlation with the H-phosphonate isomers. All chemical transformations leading from H-phosphonate diesters to boranophosphate diesters were found to be stereospecific with retention of configuration around phosphorus. The data verify our previous assignment of R(p) and S(p) isomers of dithymidine boranophosphate made on the basis of NMR and enzymatic hydrolysis.