Publications of Jiyong Hong

Papers Published

  1. Lee, J.; Hong, J.; Nam, T. G.; Peters, E. C.; Orth, A. P.; Geierstanger, B. H.; Goldfinger, L. E.; Ginsberg, M. H.; Cho C. Y.; Schultz, P. G., "A small molecule inhibitor of α4 integrin-dependent cell migration", Bioorganic & Medicinal Chemistry, 2009, 17, 977-980.
  2. Kim, H.; Kasper, A. C.; Moon, E. J.; Park, Y.; Wooten, C. M.; Dewhirst, M. W.; Hong, J., "Nucleophilic addition of organozinc reagents to 2-sulfonyl cyclic ethers: stereoselective synthesis of manassantins A and B", Organic Letters, 2009, 11(1), 89-92.
  3. Kasper, A. C.; Moon, E. J.; Hu, X.; Park, Y.; Wooten, C. M.; Kim, H.; Yang, W.; Dewhirst, M. W.; Hong, J., "Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations", Bioorganic & Medicinal Chemistry Letters, 2009, 19, 3783-3786 (Symposium-in-print honoring C. F. Barbas, 2009 Tetrahedron Young Investigator Award.).
  4. Kim, H.; Baker, J. B.; Lee, S.-U.; Park, Y.; Bolduc, K. L.; Park, H.-B.; Dickens, M. G.; Lee, D.-S.; Kim, Y.-C.; Kim, S. H.; Hong, J., "Stereoselective synthesis and osteogenic activity of subglutinols A and B", Journal of the American Chemical Society, 2009, 131(9), 3192–3194.
  5. Ying, Y.; Taori, K.; Kim, H.; Hong, J.; Luesch, H., "Total synthesis and molecular target of largazole, a histone deacetylase inhibitor", Journal of the American Chemical Society, 2008, 130(26), 8455-8459.
  6. Ying, Y.; Liu, Y.; Byeon, S. R.; Kim, H.; Luesch, H.; Hong, J., "Synthesis and activity of largazole analogues with linker and macrocycle modification", Organic Letters, 2008, 10(18), 4021-4024.
  7. Kim, D.; Lee, H.; Kim, K. W.; Park, J.; Kim, H.; Kim, S.; Hu, X.; Yang, W.; Hong, J., "A general strategy for construction of both 2,6-cis- and 2,6-trans-disubstituted tetrahydropyrans: substrate-controlled asymmetric total synthesis of (+)-scanlonenyne", Angewandte Chemie International Edition, 2008, 47(22), 4200-4203.
  8. Lee, J.; Wu, X.; Magliano, M. P.; Peters, E. C.; Wang, Y.; Hong, J.; Hebrok, M.; Ding, S.; Cho, C. Y.; Schultz, P. G., "A small molecule antagonist of the hedgehog signaling pathway", ChemBioChem, 2007, 8(16), 1916-1919.
  9. Hong, J.; Lee, J.; Min, K. H.; Walker, J. R.; Peters, E. C.; Gray, N. S.; Cho, C. Y.; Schultz, P. G., "Identification and characterization of small molecule inducers of epidermal keratinocyte differentiation", American Chemical Society Chemical Biology, 2007, 2, 171–175.
  10. Ying, Y.; Hong, J., "Synthesis of brasilibactin A and confirmation of absolute configuration of beta-hydroxy acid fragment", Tetrahedron Letters, 2007, 48(46), 8104-8107.
  11. Kim, H.; Wooten, C. M.; Park, Y.; Hong, J., "Stereoselective synthesis of tetrahydrofuran lignans via BF3•OEt2-promoted reductive deoxygenation/epimerization of cyclic hemiketal: synthesis of (–)-odoratisol C, (–)-futokadsurin A, (–)-veraguensin, (+)-fragransin A2, (+)-galbelgin, and (+)-talaumidin", Organic Letters, 2007, 9(20), 3965 - 3968.
  12. Collins, C.; Hong, J.; Sapinoso, L.; Zhou, Y.; Liu, Z.; Micklash, K.; Schultz, P. G.; Hampton, G. M., "A genetic siRNA screen for modulators of tumor cell motility identifies MAP4K4 as a pro-migratory kinase", Proceedings of the National Academy of Sciences USA, 2006, 103(10), 3775-3780.
  13. Lee, J.; Hong, J., "First synthesis and structural elucidation of (–)-presphaerene", Journal of Organic Chemistry, 2004, 69(19), 6433–6440.
  14. Boger, D. L.; Hong, J., "Asymmetric total synthesis of ent-(-)-roseophilin: assignment of absolute configuration", Journal of the American Chemical Society, 2001, 123(35), 8515-8519.
  15. Boger, D. L.; Hong, J.; Hikota, M.; Ishida, M., "Total synthesis of phomazarin", Journal of the American Chemical Society, 1999, 121(11), 2471-2477.
  16. Boger, D. L.; Hong, J., "Total synthesis of nothapodytine B and (-)-mappicine", Journal of the American Chemical Society, 1998, 120(6), 1218-1222.
  17. Kim, D.; Choi, W. J.; Hong, J. Y.; Park, I. Y.; Kim, Y. B., "An asymmetric synthesis of (+)-isonitramine by ‘triple allylic strain-controlled’ intramolecular SN2' alkylation", Tetrahedron Letters, 1996, 37(9), 1433–1434.

Papers Accepted

  1. Kim, H.; Park, Y.; Hong, J., "Stereoselective synthesis of 2,6-cis-tetrahydropyrans via tandem allylic oxidation/oxa-Michael reaction promoted by gem-disubstituent effect: stereoselective synthesis of (+)-neopeltolide macrolactone.", Angewandte Chemie International Edition, 2009.
  2. Yuan, L.; Seo, J.-S; Kang, N.; Keinan, S.; Steele, S. E.; Michelotti, G. A.; Wetsel, W. C.; Beratan, D. N.; Gong, Y.-D.; Lee, T. H.; Hong, J., "Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse", Molecular Biosystems, 2009 (Emerging Investigators Issue.).
  3. Kasper, A. C.; Baker, J. B.; Kim, H.; Hong, J., "The end game of chemical genetics: target identification", Future Medicinal Chemistry, 2009 (Review.).

Other

  1. Luesch, H.; Hong, J., "Methods and preparation of macrocyclic compounds (US Provisional Patent)", 2008.
  2. "Manassantin compounds and methods of making and using same technical field (US Provisional Patent)", 2008.
  3. Hampton, G. M.; Hong, J.; Collins, C., "Methods and compositions for modulating cell motility and inhibiting tumor metastasis", 2007 (PCT Int. Appl., 40pp. CODEN: PIXXD2 WO 2007056604.).
  4. Micklash, K. J.; Hong, J.; Mainquist, J. K.; Ding, S.; Downs, R. C.; Schultz, P. G., "Automated cellular assaying systems and related components and methods", 2007 (U.S. Pat. Appl. Publ., 63pp. CODEN: USXXCO US 2007105214.).
  5. Hong, J.; Gray, N. S.; Schultz, P. G., "Preparation of substituted pyrrolo[2,3-d]pyrimidines as inducers of keratinocyte differentiation", 2005 (PCT Int. Appl., 53pp. CODEN: PIXXD2; WO 2005107760.).