Publications [#234621] of Ross A. Widenhoefer
Journal Articles
- Lee, SD; Timmerman, JC; Widenhoefer, RA, "Enantioselective intramolecular hydroamination of unactivated alkenes catalyzed by mono- and bis(gold) phosphine complexes", Advanced Synthesis and CatalysisOctober,, 2014, 356(14-15), 3187-3192, Wiley-VCH Verlag [doi].
(last updated on 2024/04/23)Abstract:
A 1:2 mixture of (P1)(AuCl)2[P1=(S)-DTBM-MeO-BIPHEP] and silver tetrafluoroborate (AgBF4) in methanol catalyzes the intramolecular hydroamination of unactivated alkenes with carbamates and ureas to form pyrrolidine derivatives with up to 85% ee.