Publications [#232212] of Stephen L Craig

Journal Articles

  1. Craig, SL; Lin, S; Chen, J; Rebek, J, "An NMR study of the rates of single-molecule exchange in a cylindrical host capsule.", Journal of the American Chemical SocietyJuly,, 2002, 124(30), 8780-8781 [doi].
    (last updated on 2024/04/25)

    Abstract:
    Self-assembled cylindrical capsule 1 is reversibly formed from dimerization of two tetraimide resorcinarenes. Studies of guest exchange involving host capsule 1 reveal a mechanistic continuum for exchange that depends on the structure of the guest. Kinetic and dynamic NMR measurements demonstrate the direct displacement of one guest by another. Surprisingly, in the case of benzene exchange in the pairwise encapsulation of benzene and p-xylene, the incoming benzene occupies the same half of the capsule as the outgoing benzene. As the size of the guests increases, solvent-bridged intermediates determine the rates; empty volumes on the molecular scale need not be invoked.