Publications [#262984] of Tuan Vo-Dinh

Papers Published

  1. Vo-Dinh, T; Nolan, T; Cheng, YF; Sepaniak, MJ; Alarie, JP, "Phase-resolved fiber-optics fluoroimmunosensor", Applied SpectroscopyJanuary,, 1990, 44(1), 128-132, SAGE Publications [doi].
    (last updated on 2024/04/24)

    Abstract:
    This paper describes the development and application of a phase-resolved fiber-optics fluoroimmunosensor (PR-FIS), which combines the biochemical specificity of antigen-antibody reaction, the high sensitivity of laser excitation, the versatility of fiber-optics sensors, and the selectivity of phase-resolved detection. The PR-FIS device can differentiate benzo(a)pyrene and benzo(a)pyrene tetrol, a DNA-adduct product of the carcinogen benzo(a)pyrene. Benzo(a)pyrene tetrol can be detected at femtomole levels in the presence of an amount of interfacing benzo(a)pyrene that is 50-fold more concentrated.