Publications [#62725] of Tuan Vo-Dinh

Papers Published

  1. Yan, Fei and Wabuyele, Musundi B. and Griffin, Guy D. and Vo-Dinh, Tuan, "Metallic nanostructures for plasmonic sensors using surface-enhanced fluorescence and Raman detection", Proceedings of SPIE - The International Society for Optical Engineering, 2004, 5327, 53 - 59 [12.542455].
    (last updated on 2007/04/14)

    Abstract:
    We present the fabrication and characterization of silver island films with SiO2 coatings for application in plasmonic sensors based on surface-enhanced fluorescence and Raman detection. The emission spectral properties of goat anti-mouse immunoglobulin (IgG) F(ab prime )2 labeled with one or two fluorescein residues were examined on substrates with metallic silver islands. The self-quenching of fluorescein emission was mostly eliminated when this antibody fragment was held 60-90 A from the surface of metallic silver islands, and our preliminary experiments demonstrated an 8-fold emission intensity increase. Similar surfaces were also examined for surface-enhanced Raman analysis of Rhodamine 123, a potential drug for photodynamic therapy.