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Publications [#331530] of Mohamed A. Noor

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Peer-reviewed journal articles published

  1. Ballinger, MA; Noor, MAF. "Are Lethal Alleles Too Abundant in Humans?." Trends in Genetics : Tig 34.2 (February, 2018): 87-89. [doi]
    (last updated on 2019/07/18)

    Across species, many individuals carry one or more recessive lethal alleles, posing an evolutionary conundrum for their persistence. Using a population genomic approach, Amorim et al. studied the abundance of lethal disease-causing mutations in humans and found that, while appearing more common than expected, most may nonetheless persist at frequencies predicted by mutation-selection balance.