Bastiaan Driehuys, Associate Research Professor of Radiology and Physics  

Office Location: 161I Bryan Research
Office Phone: (919) 684-7786
Email Address: bastiaan.driehuys@duke.edu
Web Page: http://faculty.duhs.duke.edu/faculty/info?pid=12292

Education:
Ph.D., Princeton University, 1995

Representative Publications   (More Publications)

  1. B Driehuys, S Martinez-Jimenez, ZI Cleveland, GM Metz, DM Beaver, JC Nouls, SS Kaushik, R Firszt, C Willis, KT Kelly, J Wolber, M Kraft, HP McAdams, Chronic obstructive pulmonary disease: safety and tolerability of hyperpolarized 129Xe MR imaging in healthy volunteers and patients., Radiology, vol. 262 no. 1 (January, 2012), pp. 279-89 [doi]  [abs].
  2. HE Möller, ZI Cleveland, B Driehuys, Relaxation of hyperpolarized 129Xe in a deflating polymer bag., Journal of magnetic resonance (San Diego, Calif. : 1997), vol. 212 no. 1 (September, 2011), pp. 109-15 [doi]  [abs].
  3. AC Thomas, JC Nouls, B Driehuys, JW Voltz, B Fubara, J Foley, JA Bradbury, DC Zeldin, Ventilation defects observed with hyperpolarized 3He magnetic resonance imaging in a mouse model of acute lung injury., American journal of respiratory cell and molecular biology, vol. 44 no. 5 (May, 2011), pp. 648-54 [doi]  [abs].
  4. SS Kaushik, ZI Cleveland, GP Cofer, G Metz, D Beaver, J Nouls, M Kraft, W Auffermann, J Wolber, HP McAdams, B Driehuys, Diffusion-weighted hyperpolarized 129Xe MRI in healthy volunteers and subjects with chronic obstructive pulmonary disease., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 65 no. 4 (April, 2011), pp. 1154-65 [doi]  [abs].
  5. J Nouls, M Fanarjian, L Hedlund, B Driehuys, A Constant-Volume Ventilator and Gas Recapture System for Hyperpolarized Gas MRI of Mouse and Rat Lungs., Concepts in magnetic resonance. Part B, Magnetic resonance engineering, vol. 39B no. 2 (April, 2011), pp. 78-88 [doi] .
  6. W Zheng, ZI Cleveland, HE Möller, B Driehuys, Gradient-induced longitudinal relaxation of hyperpolarized noble gases in the fringe fields of superconducting magnets used for magnetic resonance., Journal of magnetic resonance (San Diego, Calif. : 1997), vol. 208 no. 2 (February, 2011), pp. 284-90 [doi]  [abs].
  7. SS Kaushik, ZI Cleveland, GP Cofer, G Metz, D Beaver, J Nouls, M Kraft, W Auffermann, J Wolber, HP McAdams, B Driehuys, Diffusion-weighted hyperpolarized (129)Xe MRI in healthy volunteers and subjects with chronic obstructive pulmonary disease., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine (December, 2010) [doi]  [abs].
  8. NN Mistry, A Thomas, SS Kaushik, GA Johnson, B Driehuys, Quantitative analysis of hyperpolarized 3He ventilation changes in mice challenged with methacholine., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 63 no. 3 (March, 2010), pp. 658-66 [doi]  [abs].
  9. RT Branca, ZI Cleveland, B Fubara, CS Kumar, RR Maronpot, C Leuschner, WS Warren, B Driehuys, Molecular MRI for sensitive and specific detection of lung metastases., Proceedings of the National Academy of Sciences of the United States of America, vol. 107 no. 8 (February, 2010), pp. 3693-7 [doi]  [abs].
  10. ZI Cleveland, GP Cofer, G Metz, D Beaver, J Nouls, SS Kaushik, M Kraft, J Wolber, KT Kelly, HP McAdams, B Driehuys, Hyperpolarized Xe MR imaging of alveolar gas uptake in humans., PloS one, vol. 5 no. 8 (2010), pp. e12192 [doi]  [abs].
  11. ZI Cleveland, HE Möller, LW Hedlund, B Driehuys, Continuously infusing hyperpolarized 129Xe into flowing aqueous solutions using hydrophobic gas exchange membranes., The journal of physical chemistry. B, vol. 113 no. 37 (September, 2009), pp. 12489-99 [doi]  [abs].
  12. B Driehuys, HE Möller, ZI Cleveland, J Pollaro, LW Hedlund, Pulmonary perfusion and xenon gas exchange in rats: MR imaging with intravenous injection of hyperpolarized 129Xe., Radiology, vol. 252 no. 2 (August, 2009), pp. 386-93 [doi]  [abs].
  13. AC Thomas, EN Potts, BT Chen, DM Slipetz, WM Foster, B Driehuys, A robust protocol for regional evaluation of methacholine challenge in mouse models of allergic asthma using hyperpolarized 3He MRI., NMR in biomedicine, vol. 22 no. 5 (June, 2009), pp. 502-15 [doi]  [abs].
  14. B Driehuys, HE Möller, ZI Cleveland, J Pollaro, LW Hedlund, Pulmonary Perfusion and Xenon Gas Exchange in Rats: MR Imaging with Intravenous Injection of Hyperpolarized 129Xe., Radiology (April, 2009) [doi]  [abs].
  15. RH Brown, CG Irvin, GB Allen 3rd, SD Shapiro, WJ Martin, MR Kolb, DM Hyde, GF Nieman, DD Cody, M Ishii, SJ Kadlecek, B Driehuys, RR Rizi, AM Wu, WA Weber, DB Stout, ATS Small Animal Imaging Subcommittee, An official ATS conference proceedings: advances in small-animal imaging application to lung pathophysiology., Proceedings of the American Thoracic Society, vol. 5 no. 5 (July, 2008), pp. 591-600 [doi] .
  16. B Driehuys, J Pollaro, GP Cofer, In vivo MRI using real-time production of hyperpolarized 129Xe., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 60 no. 1 (July, 2008), pp. 14-20 [doi]  [abs].
  17. B Driehuys, J Nouls, A Badea, E Bucholz, K Ghaghada, A Petiet, LW Hedlund, Small animal imaging with magnetic resonance microscopy., ILAR journal / National Research Council, Institute of Laboratory Animal Resources, vol. 49 no. 1 (2008), pp. 35-53  [abs].
  18. B Driehuys, J Walker, J Pollaro, GP Cofer, N Mistry, D Schwartz, GA Johnson, 3He MRI in mouse models of asthma., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 58 no. 5 (November, 2007), pp. 893-900 [doi]  [abs].
  19. B Driehuys, LW Hedlund, Imaging techniques for small animal models of pulmonary disease: MR microscopy., Toxicologic pathology, vol. 35 no. 1 (January, 2007), pp. 49-58 [doi]  [abs].
  20. B Driehuys, GP Cofer, J Pollaro, JB Mackel, LW Hedlund, GA Johnson, Imaging alveolar-capillary gas transfer using hyperpolarized 129Xe MRI., Proceedings of the National Academy of Sciences of the United States of America, vol. 103 no. 48 (November, 2006), pp. 18278-83 [doi]  [abs].
  21. B Driehuys, Chemistry. Toward molecular imaging with xenon MRI., Science (New York, N.Y.), vol. 314 no. 5798 (October, 2006), pp. 432-3 [doi] .
  22. ZZ Spector, K Emami, MC Fischer, J Zhu, M Ishii, V Vahdat, J Yu, S Kadlecek, B Driehuys, DA Lipson, W Gefter, J Shrager, RR Rizi, Quantitative assessment of emphysema using hyperpolarized 3He magnetic resonance imaging., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 53 no. 6 (June, 2005), pp. 1341-6 [doi]  [abs].
  23. ZZ Spector, K Emami, MC Fischer, J Zhu, M Ishii, J Yu, S Kadlecek, B Driehuys, RA Panettieri, DA Lipson, W Gefter, J Shrager, RR Rizi, A small animal model of regional alveolar ventilation using HP 3He MRI1., Academic radiology, vol. 11 no. 10 (October, 2004), pp. 1171-9 [doi]  [abs].
  24. S Månsson, J Wolber, B Driehuys, P Wollmer, K Golman, Characterization of diffusing capacity and perfusion of the rat lung in a lipopolysaccaride disease model using hyperpolarized 129Xe., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 50 no. 6 (December, 2003), pp. 1170-9 [doi]  [abs].
  25. E Babcock, I Nelson, S Kadlecek, B Driehuys, LW Anderson, FW Hersman, TG Walker, Hybrid spin-exchange optical pumping of 3He., Physical review letters, vol. 91 no. 12 (September, 2003), pp. 123003  [abs].
  26. B Chann, IA Nelson, LW Anderson, B Driehuys, TG Walker, 129Xe-Xe molecular spin relaxation., Physical review letters, vol. 88 no. 11 (March, 2002), pp. 113201  [abs].
  27. K Ruppert, JR Brookeman, KD Hagspiel, B Driehuys, JP Mugler 3rd, NMR of hyperpolarized (129)Xe in the canine chest: spectral dynamics during a breath-hold., NMR in biomedicine, vol. 13 no. 4 (June, 2000), pp. 220-8  [abs].
  28. XJ Chen, HE Möller, MS Chawla, GP Cofer, B Driehuys, LW Hedlund, GA Johnson, Spatially resolved measurements of hyperpolarized gas properties in the lung in vivo. Part I: diffusion coefficient., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 42 no. 4 (October, 1999), pp. 721-8  [abs].
  29. XJ Chen, HE Möller, MS Chawla, GP Cofer, B Driehuys, LW Hedlund, JR MacFall, GA Johnson, Spatially resolved measurements of hyperpolarized gas properties in the lung in vivo. Part II: T *(2)., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 42 no. 4 (October, 1999), pp. 729-37  [abs].
  30. A Stith, TK Hitchens, DP Hinton, SS Berr, B Driehuys, JR Brookeman, RG Bryant, Consequences of (129)Xe-(1)H cross relaxation in aqueous solutions., Journal of magnetic resonance (San Diego, Calif. : 1997), vol. 139 no. 2 (August, 1999), pp. 225-31 [doi]  [abs].
  31. HE Möller, MS Chawla, XJ Chen, B Driehuys, LW Hedlund, CT Wheeler, GA Johnson, Magnetic resonance angiography with hyperpolarized 129Xe dissolved in a lipid emulsion., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 41 no. 5 (May, 1999), pp. 1058-64  [abs].
  32. HE Möller, XJ Chen, MS Chawla, GP Cofer, B Driehuys, LW Hedlund, SA Suddarth, GA Johnson, Sensitivity and resolution in 3D NMR microscopy of the lung with hyperpolarized noble gases., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 41 no. 4 (April, 1999), pp. 800-8  [abs].
  33. HE Möller, XJ Chen, MS Chawla, B Driehuys, LW Hedlund, GA Johnson, Signal dynamics in magnetic resonance imaging of the lung with hyperpolarized noble gases., Journal of magnetic resonance (San Diego, Calif. : 1997), vol. 135 no. 1 (November, 1998), pp. 133-43 [doi]  [abs].
  34. GA Johnson, G Cates, XJ Chen, GP Cofer, B Driehuys, W Happer, LW Hedlund, B Saam, MD Shattuck, J Swartz, Dynamics of magnetization in hyperpolarized gas MRI of the lung., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 38 no. 1 (July, 1997), pp. 66-71  [abs].
  35. JP Mugler 3rd, B Driehuys, JR Brookeman, GD Cates, SS Berr, RG Bryant, TM Daniel, EE de Lange, JH Downs 3rd, CJ Erickson, W Happer, DP Hinton, NF Kassel, T Maier, CD Phillips, BT Saam, KL Sauer, ME Wagshul, MR imaging and spectroscopy using hyperpolarized 129Xe gas: preliminary human results., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, vol. 37 no. 6 (June, 1997), pp. 809-15  [abs].
  36. JR MacFall, HC Charles, RD Black, H Middleton, JC Swartz, B Saam, B Driehuys, C Erickson, W Happer, GD Cates, GA Johnson, CE Ravin, Human lung air spaces: potential for MR imaging with hyperpolarized He-3., Radiology, vol. 200 no. 2 (August, 1996), pp. 553-8  [abs].
  37. RD Black, HL Middleton, GD Cates, GP Cofer, B Driehuys, W Happer, LW Hedlund, GA Johnson, MD Shattuck, JC Swartz, In vivo He-3 MR images of guinea pig lungs., Radiology, vol. 199 no. 3 (June, 1996), pp. 867-70  [abs].
  38. B Driehuys, GD Cates, W Happer, Surface relaxation mechanisms of laser-polarized 129Xe., Physical review letters, vol. 74 no. 24 (June, 1995), pp. 4943-4946 .
  39. MS Albert, GD Cates, B Driehuys, W Happer, B Saam, CS Springer Jr, A Wishnia, Biological magnetic resonance imaging using laser-polarized 129Xe., Nature, vol. 370 no. 6486 (July, 1994), pp. 199-201 [doi]  [abs].
  40. AS Barton, NR Newbury, GD Cates, B Driehuys, H Middleton, B Saam, Self-calibrating measurement of polarization-dependent frequency shifts from Rb-3He collisions., Physical review. A, vol. 49 no. 4 (April, 1994), pp. 2766-2770 .
  41. M Gatzke, GD Cates, B Driehuys, D Fox, W Happer, B Saam, Extraordinarily slow nuclear spin relaxation in frozen laser-polarized 129Xe., Physical review letters, vol. 70 no. 5 (February, 1993), pp. 690-693 .