Abstract:
We present a DNA nanostructure, the three-
helix bundle (3HB), which consists of three
double helical DNA domains connected by six
immobile crossover junctions such that the
helix axes are not coplanar. The 3HB motif
presents a triangular cross-section with one
helix lying in the groove formed by the other
two. By differential programming of sticky-
ends, 3HB tiles can be arrayed in two
distinct lattice conformations:
one-dimensional filaments and two-dimensional
lattices. Filaments and lattices have been
visualized by high-resolution, tapping mode
atomic force microscopy (AFM) under buffer.
Their dimensions are shown to be in excellent
agreement with designed structures. We also
demonstrate an electroless chemical
deposition for fabricating metallic nanowires
templated on self-assembled filaments. The
metallized nanowires have diameters down to
20 nm and display Ohmic current-voltage
characteristic.
Duke University * Arts & Sciences * Physics * Faculty * Staff * Grad * Researchers * Reload * Login
Copyright (c) 2001-2002 by Duke University Physics.