James T. Dobbins, Professor of Radiology and Biomedical Engineering and Physics  

James T. Dobbins

Office Location: 2424 Erwin Road, Suite 302, Ravin Advanced Imaging Labs, Durham, NC 27705
Email Address: james.dobbins@duke.edu
Web Page: http://faculty.duhs.duke.edu/faculty/info?pid=470

Specialties:
Medical Imaging

Education:
Ph.D., University of Wisconsin at Madison, 1985
M.S., University of Wisconsin at Madison, 1983
B.S., University of North Carolina at Chapel Hill, 1978

Representative Publications   (More Publications)

  1. E Samei, N Majdi-Nasab, JT Dobbins and HP McAdams, Biplane correlation imaging: a feasibility study based on phantom and human data., J Digit Imaging, vol. 25 no. 1 (February, 2012), pp. 137-147 [21618054], [doi]  [abs].
  2. JT Dobbins, E Samei, NT Ranger and Y Chen, Intercomparison of methods for image quality characterization. II. Noise power spectrum., Med Phys, vol. 33 no. 5 (May, 2006), pp. 1466-1475 [16752581]  [abs].
  3. CM Hsu, ML Palmeri, WP Segars, AI Veress and JT Dobbins, An analysis of the mechanical parameters used for finite element compression of a high-resolution 3D breast phantom., Med Phys, vol. 38 no. 10 (October, 2011), pp. 5756-5770 [21992390], [doi]  [abs].
  4. DJ Godfrey, HP McAdams and JT Dobbins, Optimization of the matrix inversion tomosynthesis (MITS) impulse response and modulation transfer function characteristics for chest imaging., Med Phys, vol. 33 no. 3 (March, 2006), pp. 655-667 [16878569]  [abs].
  5. E Samei, NT Ranger, JT Dobbins and CE Ravin, Effective dose efficiency: an application-specific metric of quality and dose for digital radiography., Phys Med Biol, vol. 56 no. 16 (August, 2011), pp. 5099-5118 [21775791], [doi]  [abs].
  6. Dobbins, J.T., III and Godfrey, D.J., Digital x-ray tomosynthesis: current state of the art and clinical potential, Phys. Med. Biol. (UK), vol. 48 no. 19 (2003), pp. 65 - 106 [R01]  [abs].
  7. Dobbins JT 3rd, McAdams HP. Digital tomosynthesis. In Advances in Medical Physics 2010. Wolbarst AB, Mossman KL, Hendee WR (eds). Medical Physics Publishing, Madison, Wisconsin, 2010 (in press) .
  8. Warp, R.J. and Dobbins, J.T., III, Quantitative evaluation of noise reduction strategies in dual-energy imaging, Med. Phys. (USA), vol. 30 no. 2 (2003), pp. 190 - 8 [1.1538232]  [abs].
  9. JT Dobbins and HP McAdams, Chest tomosynthesis: technical principles and clinical update., Eur J Radiol, vol. 72 no. 2 (November, 2009), pp. 244-251 [19616909], [doi]  [abs].
  10. Dobbins, J.T., III and Ergunb, D.L. and Rutz, L. and Hinshaw, D.A. and Blume, H. and Clark, D.C., DQE(f) of four generations of computed radiography acquisition devices, Med. Phys. (USA), vol. 22 no. 10 (1995), pp. 1581 - 93 [1.597627]  [abs].
  11. E Samei, NT Ranger, A MacKenzie, ID Honey, JT Dobbins and CE Ravin, Effective DQE (eDQE) and speed of digital radiographic systems: an experimental methodology., Med Phys, vol. 36 no. 8 (August, 2009), pp. 3806-3817 [19746814]  [abs].
  12. CM Li, WP Segars, GD Tourassi, JM Boone and JT Dobbins, Methodology for generating a 3D computerized breast phantom from empirical data., Med Phys, vol. 36 no. 7 (July, 2009), pp. 3122-3131 [19673211]  [abs].
  13. JT Dobbins, Tomosynthesis imaging: at a translational crossroads., Med Phys, vol. 36 no. 6 (June, 2009), pp. 1956-1967 [19610284]  [abs].
  14. DJ Godfrey, HP McAdams and JT Dobbins, Stochastic noise characteristics in matrix inversion tomosynthesis (MITS)., Med Phys, vol. 36 no. 5 (May, 2009), pp. 1521-1532 [19544768]  [abs].
  15. Li CM, Segars WP, Lo JY, Veress AI, Boone JM, Dobbins JT 3rd. Computerized 3D breast phantom with enhanced high-resolution detail. SPIE Medical Imaging Conference. 2009;7258:0S1-OS8.
    .
  16. E Samei, NT Ranger, A MacKenzie, ID Honey, JT Dobbins and CE Ravin, Detector or system? Extending the concept of detective quantum efficiency to characterize the performance of digital radiographic imaging systems., Radiology, vol. 249 no. 3 (December, 2008), pp. 926-937 [19011189], [doi]  [abs].
  17. TD James, HP McAdams, JW Song, CM Li, DJ Godfrey, DM DeLong, SH Paik and S Martinez-Jimenez, Digital tomosynthesis of the chest for lung nodule detection: interim sensitivity results from an ongoing NIH-sponsored trial., Med Phys, vol. 35 no. 6 (June, 2008), pp. 2554-2557 [18649488]  [abs].
  18. JT Dobbins, HP McAdams, DJ Godfrey and CM Li, Digital tomosynthesis of the chest., J Thorac Imaging, vol. 23 no. 2 (May, 2008), pp. 86-92 [18520565], [doi]  [abs].
  19. Chen Y, Lo JY, Dobbins JT 3rd. Impulse response and modulation transfer function analysis for shift-and-add and back projection image reconstruction algorithms in digital breast tomosynthesis (DBT). Int. J. of Functional Informatics and Personalised Medicine. 2008;1(2):189-204.
    .
  20. Li CM, Segars WP, Lo JY, Veress AI, Boone JM, Dobbins JT 3rd. Three-dimensional computer generated breast phantom based on empirical data. SPIE Medical Imaging Conference. 2008;6913:14.1-14.8.
    .
  21. Y Chen, JY Lo and JT Dobbins, Importance of point-by-point back projection correction for isocentric motion in digital breast tomosynthesis: relevance to morphology of structures such as microcalcifications., Med Phys, vol. 34 no. 10 (October, 2007), pp. 3885-3892 [17985634]  [abs].
  22. NT Ranger, E Samei, JT Dobbins and CE Ravin, Assessment of detective quantum efficiency: intercomparison of a recently introduced international standard with prior methods., Radiology, vol. 243 no. 3 (June, 2007), pp. 785-795 [17517933], [doi]  [abs].
  23. E Samei, SA Stebbins, JT Dobbins, HP McAdams and JY Lo, Multiprojection correlation imaging for improved detection of pulmonary nodules., AJR Am J Roentgenol, vol. 188 no. 5 (May, 2007), pp. 1239-1245 [17449766], [doi]  [abs].
  24. HP McAdams, E Samei, J Dobbins, GD Tourassi and CE Ravin, Recent advances in chest radiography., Radiology, vol. 241 no. 3 (December, 2006), pp. 663-683 [17114619], [doi]  [abs].
  25. JT Dobbins 3rd, E Samei, NT Ranger, Y Chen, Intercomparison of methods for image quality characterization. II. Noise power spectrum., Medical physics, vol. 33 no. 5 (May, 2006), pp. 1466-75  [abs].
  26. E Samei, NT Ranger, JT Dobbins 3rd, Y Chen, Intercomparison of methods for image quality characterization. I. Modulation transfer function., Medical physics, vol. 33 no. 5 (May, 2006), pp. 1454-65  [abs].
  27. DJ Godfrey, HP McAdams, JT Dobbins 3rd, Optimization of the matrix inversion tomosynthesis (MITS) impulse response and modulation transfer function characteristics for chest imaging., Medical physics, vol. 33 no. 3 (March, 2006), pp. 655-67  [abs].
  28. Chen Y, Lo JY, Baker JA, Dobbins JT 3rd. Gaussian frequency blending algorithm with matrix inversion tomosynthesis (MITS) and filtered back projection (FBP) for better digital breast tomosynthesis reconstruction. SPIE Medical Imaging Conference. 2006;6142:0E1-0E9. .
  29. Baydush AH, Godfrey DJ, Oldham M, Dobbins JT III: Initial application of digital tomosynthesis with on-board imaging in radiation oncology. Proc. SPIE Medical Imaging Symposium. 2005;5745:1300-1305. .
  30. Bissonnette M, Hansroul M, Masson E, Savard S, Cadieux S, Warmoes P, Gravel D, Agopyan J, Polischuk B, Haerer W, Mertelmeier T, Lo JY, Chen Y, Dobbins JT III, Jesneck JL and Singh S: Digital breast tomosynthesis using an amorphous selenium flat panel detector. Proc. SPIE Medical Imaging Symposium. 2005;5745:529-540. .
  31. Chen Y, Dobbins JT III: Impulse response analysis for several digital tomosynthesis mammography reconstruction algorithms. Proc. SPIE Medical Imaging Symposium. 2005;5745:541-549. .
  32. Dobbins JT III, Samei E, Ranger NT, Chen Y:  Inter-comparison of methods for image quality comparison:  2. Noise power spectrum.  Medical Physics (submitted), 2005. .
  33. Godfrey DJ, McAdams HP, Dobbins JT III:  Averaging adjacent planes for artifact reduction in matrix inversion tomosynthesis (MITS).  Medical Physics (submitted), 2005. .
  34. Godfrey DJ, McAdams HP, Dobbins JT III:  Optimization of the matrix inversion tomosynthesis (MITS) impulse response and modulation transfer function characteristics for chest imaging.  Medical Physics (submitted), 2005. .
  35. Godfrey DJ, McAdams HP, Dobbins JT III:  Stochastic noise characteristics in matrix inversion tomosynthesis (MITS).  Medical Physics (submitted), 2005. .
  36. Ranger NT, Samei E, Dobbins JT III, Ravin CE:  Inter-comparison of methods for image quality comparison:  3. Detective quantum efficiency.  Medical Physics (submitted), 2005. .
  37. Ranger NT, Samei E, Dobbins JT III,  Ravin CE:  Measurement of the detective quantum efficiency in digital detectors consistent with the IEC 62220-1 standard:  practical considerations regarding the choice of filter material.  Medical Physics (accepted 2005). .
  38. Samei E, Dobbins JT III, Lo JY, Tornai M:  A framework for optimizing the radiographic technique in digital x-ray imaging.  Radiation Protection Dosimetry (accepted 2005). .
  39. Samei E, Dobbins JT III, Ranger NT, Chen Y:  Inter-comparison of methods for image quality comparison:  1. Modulation transfer function.  Medical Physics (submitted), 2005. .
  40. E Samei, RS Saunders, JY Lo, JT Dobbins, JL Jesneck, CE Floyd and CE Ravin, Fundamental imaging characteristics of a slot-scan digital chest radiographic system., Med Phys, vol. 31 no. 9 (September, 2004), pp. 2687-2698 [15487752]  [abs].
  41. Samei E, Lo JY, Yoshizumi T, Jesneck J, Dobbins JT III, Floyd CE Jr, McAdams HP, Ravin CE. Comparative scatter and dose performance of slot-scan and wide-beam digital chest radiographic systems.  Radiology  (accepted) 2004. .
  42. JT Dobbins and DJ Godfrey, Digital x-ray tomosynthesis: current state of the art and clinical potential., Phys Med Biol, vol. 48 no. 19 (October, 2003), pp. R65-106 [14579853]  [abs].
  43. J Duryea, JT Dobbins and JA Lynch, Digital tomosynthesis of hand joints for arthritis assessment., Med Phys, vol. 30 no. 3 (March, 2003), pp. 325-333 [12674232]  [abs].
  44. RJ Warp and JT Dobbins, Quantitative evaluation of noise reduction strategies in dual-energy imaging., Med Phys, vol. 30 no. 2 (February, 2003), pp. 190-198 [12607836]  [abs].
  45. JT Dobbins, E Samei, HG Chotas, RJ Warp, AH Baydush, CE Floyd and CE Ravin, Chest radiography: optimization of X-ray spectrum for cesium iodide-amorphous silicon flat-panel detector., Radiology, vol. 226 no. 1 (January, 2003), pp. 221-230 [12511694], [doi]  [abs].
  46. Dobbins JT 3rd, Godfrey DJ, McAdams HP. Chest tomosynthesis. In Advances in Digital Radiography: RSNA Categorical course in Digital Radiography, Samei E, Flynn MJ (eds), Radiological Society of North America, Oak Brook, Illinois, 2003. .
  47. Dobbins JT 3rd, Warp RJ. Dual-energy methods for tissue discrimination in chest radiography. In Advances in Digital Radiography: RSNA Categorical course in Digital Radiography, Samei E, Flynn MJ (eds), Radiological Society of North America, Oak Brook, Illinois, 2003. .
  48. Godfrey DJ, Rader A, Dobbins JT 3rd. Practical strategies for the clinical implementation of matrix inversion tomosynthesis. Proc. SPIE Medical Imaging Symposium. 2003;5030:379-390. .
  49. Maidment ADA, Albert M, Bunch PC, Cunningham IA, Dobbins JT 3rd, Gagne RM, Nishikawa RM, Wagner RF, Van Metter RL. Standardization of NPS measurement: interim report of AAPM TG16. Proc. SPIE Medical Imaging Symposium. 2003;5030:523-532. .
  50. Nicolas FS, Rader AE, Barber MJ, Dobbins JT 3rd. System and method for synchronization of the acquisition of images with the cardiac cycle for dual energy imaging. U.S. Patent # 6,643,536, 2003. Assignees: GE Medical Systems Global Technology Company and Duke University. .
  51. Vyborny C, Bunch P, Chotas J, Dobbins J, Niklason L, Schaefer-Prokop C. Image quality in chest radiography. Report #70 of the International Commission on Radiation Units and Measurements (ICRU). Journal of the ICRU. 2003;3(2):1-176. .
  52. CE Floyd, RJ Warp, JT Dobbins, HG Chotas, AH Baydush, R Vargas-Voracek and CE Ravin, Imaging characteristics of an amorphous silicon flat-panel detector for digital chest radiography., Radiology, vol. 218 no. 3 (March, 2001), pp. 683-688 [11230640], [doi]  [abs].
  53. Duryea J, Dobbins JT 3rd. Application of digital tomosynthesis to hand radiography for arthritis assessment. Proc. SPIE Medical Imaging Conference. 2001;4320:688-695. .
  54. Godfrey DJ, Warp RJ, Dobbins JT 3rd. Optimization of Matrix Inversion Tomosynthesis. Proc. SPIE Medical Imaging Conference. 2001;4320:696-704. .
  55. Sabol JM, Avinash, GB, Nicolas F, Claus B, Zhao J, Dobbins JT 3rd. Development and characterization of a dual-energy subtraction imaging system for chest radiography based on CsI:Tl amorphous silicon flat-panel technology. Proc. SPIE Medical Imaging Conference. 2001;4320:399-408. .
  56. Samei EJ, Flynn MJ, Chotas HG, Dobbins JT 3rd. DQE of direct and indirect digital radiography systems. Proc. SPIE Medical Imaging Conference. 2001;4320:189-197. .
  57. Dobbins JT 3rd, Boone JM (eds). Medical Imaging 2000: Physics of Medical Imaging, SPIE, Bellingham, WA, 2000. .
  58. Dobbins JT 3rd. Image quality metrics for digital systems. In Handbook of Medical Imaging, Vol. 1, Van Metter RL, Beutel J, Kundel H (eds), SPIE Press, Bellingham, WA, 2000. .
  59. Warp RJ, Godfrey DG, Dobbins JT 3rd. Applications of Matrix Inverse Tomosynthesis. Proc. SPIE Medical Imaging Conference. 2000;3977:376-383. .
  60. HG Chotas, JT Dobbins and CE Ravin, Principles of digital radiography with large-area, electronically readable detectors: a review of the basics., Radiology, vol. 210 no. 3 (March, 1999), pp. 595-599 [10207454], [doi] .
  61. CD Bradford, WW Peppler and JT Dobbins, Performance characteristics of a Kodak computed radiography system., Med Phys, vol. 26 no. 1 (January, 1999), pp. 27-37 [9949395]  [abs].
  62. Boone JM, Dobbins JT 3rd (eds). Medical Imaging 1999: Physics of Medical Imaging, SPIE, Bellingham, WA, 1999. .
  63. Dobbins JT 3rd, Boone JM (eds). Medical Imaging 1998: Physics of Medical Imaging, SPIE, Bellingham, WA, 1998. .
  64. Dobbins JT 3rd, Hames SM, Haseqawa BH, Degrado TR, Zagzebski JA, Frayne R. Medical imaging. In Measurement, Instrumentation and Sensors Handbook, Webster JG (ed), CRC Press, Boca Raton, FL, 1998. .
  65. RJ Althof, MG Wind and JT Dobbins, A rapid and automatic image registration algorithm with subpixel accuracy., IEEE Trans Med Imaging, vol. 16 no. 3 (June, 1997), pp. 308-316 [9184893], [doi]  [abs].
  66. DA Hinshaw and JT Dobbins, Plate scatter correction for improved performance in dual-energy imaging., Med Phys, vol. 23 no. 6 (June, 1996), pp. 871-876 [8798172]  [abs].
  67. JT Dobbins, DL Ergun, L Rutz, DA Hinshaw, H Blume and DC Clark, DQE(f) of four generations of computed radiography acquisition devices., Med Phys, vol. 22 no. 10 (October, 1995), pp. 1581-1593 [8551982]  [abs].
  68. JT Dobbins, Effects of undersampling on the proper interpretation of modulation transfer function, noise power spectra, and noise equivalent quanta of digital imaging systems., Med Phys, vol. 22 no. 2 (February, 1995), pp. 171-181 [7565348]  [abs].
  69. Hinshaw DA, Dobbins JT 3rd. Recent progress in noise reduction and scatter correction in dual-energy imaging. Proc. SPIE Medical Imaging Conference. 1995 Feb;2432:134-142. .
  70. Ergun DL, Peppler WW, Dobbins JT 3rd, Zink FE, Kruger DG, Kelcz F, de Bruijn FJ, Bellers EW, Wang Y, Althof RJ, Wind MGJ. Dual-energy computed radiography: improvements in processing. Proc. SPIE Medical Imaging Conference. 1994 Feb;2167:663-671. .
  71. JT Dobbins, JJ Rice, PC Goodman, EF Patz and CE Ravin, Variable compensation chest radiography performed with a computed radiography system: design considerations and initial clinical experience., Radiology, vol. 187 no. 1 (April, 1993), pp. 55-63 [8451437], [doi]  [abs].
  72. HG Chotas, CE Floyd, JT Dobbins and CE Ravin, Digital chest radiography with photostimulable storage phosphors: signal-to-noise ratio as a function of kilovoltage with matched exposure risk., Radiology, vol. 186 no. 2 (February, 1993), pp. 395-398 [8421741], [doi]  [abs].
  73. JT Dobbins, JJ Rice, CA Beam and CE Ravin, Threshold perception performance with computed and screen-film radiography: implications for chest radiography., Radiology, vol. 183 no. 1 (April, 1992), pp. 179-187 [1549669], [doi]  [abs].
  74. Dobbins JT 3rd. Variable compensation method and apparatus for radiological images (continuation in part). U.S. Patent #5,081,659. January, 1992. Assignee: Duke University. .
  75. JT Dobbins, HG Chotas and H Benveniste, Direct digitization of optical images using a photostimulable phosphor system., Med Phys, vol. 19 no. 4 (July, 1992), pp. 1071-1080 [1518470]  [abs].
  76. HG Chotas, JT Dobbins, CE Floyd and CE Ravin, Single-exposure conventional and computed radiography image acquisition., Invest Radiol, vol. 26 no. 5 (May, 1991), pp. 438-445 [2055742]  [abs].
  77. HG Chotas, CE Floyd, JT Dobbins, JY Lo and CE Ravin, Scatter fractions in AMBER imaging., Radiology, vol. 177 no. 3 (December, 1990), pp. 879-880 [2244003], [doi]  [abs].
  78. CE Floyd, HG Chotas, JT Dobbins and CE Ravin, Quantitative radiographic imaging using a photostimulable phosphor system., Med Phys, vol. 17 no. 3 (May, 1990), pp. 454-459 [2385203]  [abs].
  79. Dobbins JT 3rd. Matrix Inversion Tomosynthesis improvements in longitudinal x-ray slice imaging. U.S. Patent #4,903,204, 1990. Assignee: Duke University. .
  80. JT Dobbins and AO Powell, Variable compensation technique for digital radiography of the chest., Radiology, vol. 173 no. 2 (November, 1989), pp. 451-458 [2798877], [doi]  [abs].
  81. Dobbins JT 3rd. Variable Compensation method and apparatus for radiological images. U.S. Patent #4,868,857, Sept. 1989. Assignee: Duke University. .
  82. Dobbins JT 3rd, Powell AO. Characterization of variable compensation radiography of the chest. Proc. Chest Imaging Conference 1987, WW Peppler and AA Alter (eds.), pp. 144-154, 1987. .
  83. BH Hasegawa, JT Dobbins, S Naimuddin, WW Peppler and CA Mistretta, Geometrical properties of a digital beam attenuator system., Med Phys, vol. 14 no. 3 (May, 1987), pp. 314-321 [3600518]  [abs].
  84. Sorenson JA, Dobbins JT 3rd. Techniques for chest radiography. Proc. Chest Imaging Conference 1987, WW Peppler and AA Alter (eds.), pp. 1-15, 1987. .
  85. BH Hasegawa, S Naimuddin, JT Dobbins, CA Mistretta, WW Peppler, NJ Hangiandreou, JT Cusma, JC McDermott, BV Kudva and KM Melbye, Digital beam attenuator technique for compensated chest radiography., Radiology, vol. 159 no. 2 (May, 1986), pp. 537-543 [3961188], [doi]  [abs].
  86. Hasegawa BH, Naimuddin S, Dobbins JT 3rd, Mistretta CA, Peppler WW, Hangiandreou NJ, Cusma JT, McDermott JC. Chest radiography using patient-specific digitally-prepared compensating filters. Proc. SPIE Conference on Medical Imaging and Instrumentation. Vol. 555, April 1985. .
  87. Hasegawa BH, Naimuddin S, Dobbins JT 3rd, Peppler WW, Van Lysel MS, Cusma JT, Lancaster JC, Hoffman P, Lee CS, Molloi S, Mistretta CA, Kudva BV, Melbye KM. Design of a digital beam attenuator system for chest radiography. Proc. SPIE Conference on Applications of Optical Instrumentation in Medicine XIII. Vol. 535, February 1985. .
  88. Lee CS, Peppler WW, Van Lysel MS, Cusma JT, Folts JD, Zarnstorff WC, Mistretta CA, Dobbins JT 3rd, Hasegawa BH, Naimuddin S, Molloi S, Hangiandreou N, Lancaster JC. Adaptive processing algorithms for intravenous digital subtraction coronary angiography. Proc. SPIE Conference on Applications of Optical Instrumentation in Medicine XIII. Vol. 535, Feb. 1985. .
  89. Mistretta CA, Peppler WW, Hasegawa BH, Dobbins JT 3rd, Kudva BV. Digitally controlled x-ray beam attenuation method and apparatus. U.S. Patent #4,497,062, January 1985. .
  90. JT Dobbins, PL Pedersen, RB Mazess, JR Cameron, JL Hansen and LV Hefner, A scanning-slit x-ray videoabsorptiometric technique for bone mineral measurement., Med Phys, vol. 11 no. 5 (September, 1984), pp. 582-588 [6503872]  [abs].
  91. Hasegawa BH, Dobbins JT 3rd, Peppler WW, Cusma JT, Kudva BV, Mistretta CA, Van Lysel MS, Lee CS, Naimuddin S, Lancaster JC, Melbye K. Feasibility of selective exposure radiography. Proc. SPIE Conference on Applications of Optical Instrumentation in Medicine XII. 1984 Feb;454:271-78. .
  92. Hasegawa BH, Dobbins JT 3rd, Peppler WW, Kudva BV, Mistretta CA, Cusma JT, Melbye KM, Van Lysel MS, Lee CS, Naimuddin S, Molloi S, Lancaster JC. Application of a digital beam attenuator to chest radiography.  Proc. SPIE Conference on Medical Imaging and Instrumentation 1984 Apr;486:2-7. .
  93. Mistretta CA, Van Lysel MS, Peppler W, Dobbins JT 3rd, Hasegawa B, Zarnstorff W, Lee CS, Naimuddin S, Myerowitz PD, Swanson D, Strother CM, Crummy AB, Sackett JF. Applicazioni attuali e aspetti tecnici della angiografia digitale. La Radiologia Medica 1984 Apr;70(4):177-84. .
  94. DK Swanson, PD Myerowitz, B Hasegawa, MS Van Lysel, KM Watson, DW Frantz, S Banaszak, E Hausman-Stokes, WW Peppler and JT Dobbins, Videodensitometric quantitation of mean blood flow., J Surg Res, vol. 34 no. 6 (June, 1983), pp. 524-532 [6855221]  [abs].
  95. MS Van Lysel, JT Dobbins, WW Peppler, BH Hasegawa, CS Lee, CA Mistretta, WC Zarnstorff, AB Crummy, W Kubal, B Bergsjordet, CM Strother and JF Sackett, Work in progress: hybrid temporal-energy subtraction in digital fluoroscopy., Radiology, vol. 147 no. 3 (June, 1983), pp. 869-874 [6342038], [doi]  [abs].
  96. Crummy AB, Stieghorst MF, Van Lysel MS, Dobbins JT 3rd. Advances in diagnosis: applying digital subtraction arteriography. J Cardiovascular Med. 1983 Mar;8(3):345-62. .
  97. Dobbins JT 3rd, Van Lysel MS, Hasegawa BH, Peppler WW, Mistretta CA. Spatial frequency filtering in digital subtraction angiography (DSA) by real-time digital video convolution. Proc. SPIE Conference on Applications of Optical Instrumentation in Medicine XI. 1983 Apr;419:111-21. .
  98. Hasegawa BH, Dobbins JT 3rd, Peppler WW, Kudva BV, Melbye K, Van Lysel MS, Lee CS, Naimuddin S, Lancaster JC, Mistretta CA. Selective exposure radiography using digitally-formed x-ray beam attenuators. Proc. SPIE Conference on Applications of Optical Instrumentation in Medicine XI. 1983 Apr;419:282-88. .
  99. Mistretta CA, Peppler WW, Van Lysel M, Dobbins JT 3rd, Hasegawa B, Myerowitz PD, Swanson D, Lee CS, Naimuddin S, Zarnstorff W, Crummy AB, Strother CM, Sackett JF. Recent advances in digital radiography. Annales de Radiologie 1983 Nov;26(7):537-42. .
  100. Peppler WW, Van Lysel MS, Dobbins JT 3rd, Lancaster JC, Hicks J, Hasegawa BH, Lee CS, Shaikh N, Zarnstorff WC, Mistretta CA, Myerowitz PD, Swanson DK. Progress report on the University of Wisconsin digital video image processor (DVIP II). Digital Imaging in Cardiovascular Radiology, Heintzen PH and Brennecke R (eds), Georg Theime Verlag, Stuttgart, 1983. .
  101. Myerowitz PD, Mistretta CA, Shaw CG, Van Lysel MS, Swanson DK, Lasser TA, Dhanani SP, Zarnstorff WC, Vander Ark CR, Dobbins JT 3rd, Peppler WW, Crummy AB. Digital cardiovascular imaging. In Coronary Artery Disease Today, Bruschke AVG, van Herpen G, Vermeulen FEE (eds), Excerpta Medica, Amsterdam, 1982. .
  102. Peppler WW, Kudva BV, Dobbins JT 3rd, Lee CS, Hasegawa BH, Van Lysel M, Mistretta CA. A digitally controlled beam attenuator. Proc. SPIE Conference on Applications of Optical Instrumentation in Medicine X. 1982 May;347:106-11. .
  103. Van Lysel MS, Zarnstorff WC, Lancaster JC, Mistretta CA, Dobbins JT 3rd. Real-time digital video recording system. Proc. SPIE Conference on Digital Radiography. 1981 Sep;314:389-95. .

Highlight:

James T. Dobbins III, PhD., FAAPM
Director, Medical Physics Graduate Program
Professor of Radiology, Biomedical Engineering, and Physics
Co-founder, Society of Directors of Academic Medical Physics Programs, Inc.

The research in my laboratory focuses on three main areas:  (1) advanced imaging applications to improve diagnostic accuracy in clinical imaging, (2) the scientific assessment of image quality, and (3) developing lower cost imaging for the developing world.

Projects in the area of advanced imaging applications have included applications of dual-energy and digital tomosynthesis for improving detection of cancer in chest and breast imaging.  We are the leading laboratory in the world in the application of tomosynthesis to thoracic imaging applications, and were the first to demonstrate that tomosynthesis can triple the detection sensitivity of pulmonary nodules over conventional chest radiography.  We have had four NIH R01 grants funded to develop, optimize, and perform clinical studies of dual-energy and tomosynthesis imaging; commercial products in both these modalities are now available around the world as a result of our laboratory’s efforts.

My lab’s work in the science of image quality analysis has included substantial effort in the theory and experimental measurement of modulation transfer function, noise power spectrum, and detective quantum efficiency in undersampled digital systems.  We received the Sylvia Sorkin Greenfield award in 1996 for the best publication of the year in the journal Medical Physics as a result of this work.

Current projects include the development of a new noise reduction technique called Correlated-Polarity Noise Reduction for improvement of image quality and reduction of dose in CT imaging, and the development of a lower-cost CT scanner for the developing world.

In addition to these research interests, I also serve as the Director of the Medical Physics Graduate Program at Duke, which includes over 50 faculty and 50 MS and PhD students training in diagnostic imaging physics, radiation oncology physics, nuclear medicine physics, and medical health physics.

Current Ph.D. Students   (Former Students)

  • Christina M. Li  
Postdocs Mentored

  • Nariman Majdi-Nasab (2004 - 2006)  
  • Sean M Hames (1996 - 1998)  
  • Dean A Hinshaw (1993 - 1995)  
Selected Invited Lectures

  1. Theoretical and practical elements of tomosynthesis imaging (invited workshop), 2007, SPIE Physics of Medical Imaging Conference    
  2. Imaging in Medicine: digital radiography (keynote address), 2006, SPIE Physics of Medical Imaging Conference    
  3. Digital radiography: technical foundations and contemporary research, 2005, Memphis BioImaging Symposium    
  4. Advances in digital radiography -- Digital radiographic advanced methods for depth discrimination: chest tomosynthesis, 2005, Radiological Society of North America 91st Scientific Assembly    
  5. Digital x-ray detectors for radiography: technical innovations (physics plenary talk), 1999, Radiological Society of North America 85th Scientific Assembly