Publications [#328129] of Ehsan Samei

Papers Published
  1. Fu, W; Sturgeon, GM; Agasthya, G; Segars, WP; Kapadia, AJ; Samei, E, Breast dose reduction with organ-based, wide-angle tube current modulated CT., Journal of medical imaging (Bellingham, Wash.), vol. 4 no. 3 (July, 2017), pp. 031208 [doi] .

    Abstract:
    This study aimed to estimate the organ dose reduction potential for organ-dose-based tube current modulated (ODM) thoracic computed tomography (CT) with a wide dose reduction arc. Twenty-one computational anthropomorphic phantoms (XCAT) were used to create a virtual patient population with clinical anatomic variations. The phantoms were created based on patient images with normal anatomy (age range: 27 to 66 years, weight range: 52.0 to 105.8 kg). For each phantom, two breast tissue compositions were simulated: [Formula: see text] and [Formula: see text] (glandular-to-adipose ratio). A validated Monte Carlo program (PENELOPE, Universitat de Barcelona, Spain) was used to estimate the organ dose for standard tube current modulation (TCM) (SmartmA, GE Healthcare) and ODM (GE Healthcare) for a commercial CT scanner (Revolution, GE Healthcare) using a typical clinical thoracic CT protocol. Both organ dose and [Formula: see text]-to-organ dose conversion coefficients ([Formula: see text] factors) were compared between TCM and ODM. ODM significantly reduced all radiosensitive organ doses ([Formula: see text]). The breast dose was reduced by [Formula: see text]. For [Formula: see text] factors, organs in the anterior region (e.g., thyroid and stomach) exhibited substantial decreases, and the medial, distributed, and posterior region saw either an increase of less than 5% or no significant change. ODM significantly reduced organ doses especially for radiosensitive superficial anterior organs such as the breasts.