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Publications [#119468] of Darrell V Lewis Jr.

Papers Published

1. WW Anderson, DV Lewis, HS Swartzwelder, WA Wilson, Magnesium-free medium activates seizure-like events in the rat hippocampal slice., Brain research, NETHERLANDS, vol. 398 no. 1 (November, 1986), pp. 215-9, ISSN 0006-8993
   (last updated on 2006/10/24)

   Abstract:
   The effect of magnesium-free medium on the electrical activity in CA3 of the rat hippocampal slice was examined. Magnesium removal resulted in the development of spontaneous and triggered interictal-like bursting, followed by spontaneous ictal-like events and finally periodic clustered bursts. The ictal-like events consisted of a tonic firing phase and a phase of clustered burst discharges resembling the tonic and clonic phases of seizures. The return to normal medium resulted in spontaneous and triggered interictal-like bursts.

   Keywords:
   Action Potentials • Age Factors • Animals • Electric Stimulation • Hippocampus • Magnesium • Male • Rats • Rats, Inbred Strains • Seizures • pharmacology* • physiology • physiopathology*