Paul M. Magwene, Professor of Biology

Please note: Paul has left Center for Theoretical & Mathematical Sciences at Duke University; some info here might not be up to date.

Contact Info:

Office Location:	124 Science Drive, Room 4103 Ffsc, Duke Box 90338, Durham, NC 27708
Office Phone:	(919) 613-8159
Email Address:
Web Pages:	http://biology.duke.edu/magwenelab http://magwenelab.org

Teaching (Fall 2025):

• BIOLOGY 724D-1.001, DATA SCIENCE FOR BIOLOGISTS I Synopsis

  FFSC 4233, Tu 03:05 PM-05:35 PM

• BIOLOGY 724D-1.01D, DATA SCIENCE FOR BIOLOGISTS I Synopsis

  Bio Sci 144, Th 12:00 PM-01:00 PM

Education:

Ph.D.	The University of Chicago	1999
AB	Harvard College	1993

Specialties:

Genomics
Evolution
Genetics

Research Interests: Evolutionary Genomics and Bioinformatics

Keywords:

Adaptation, Biological • Biofilms • bioinformatics • Biological Evolution • Computational Biology • Cyclic AMP-Dependent Protein Kinases • evolution • Evolution, Molecular • Genetic Association Studies • Genetic Variation • genetics • Genome, Fungal • genomics • Genomics • Genotype • Models, Biological • Models, Statistical • Multivariate Analysis • networks • Quantitative Trait Loci • theory

Current Ph.D. Students   (Former Students)

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Postdocs Mentored

• Daniel Skelly (2013 - present)  
• Helen Murphy (2013 - 2014)  
• Jennifer Reininga-Craven (2009 - 2011)  
• Josh Granek (2007 - 2012)  

Recent Publications   (More Publications)

1. Montoya, MC; Wilhoit, K; Murray, D; Perfect, JR; Magwene, PM, Genome restructuring and lineage diversification of Cryptococcus neoformans during chronic infection of human hosts., medRxiv (February, 2025) [doi]  [abs]
2. Huang, J; Larmore, CJ; Priest, SJ; Xu, Z; Dietrich, FS; Yadav, V; Magwene, PM; Sun, S; Heitman, J, Distinct evolutionary trajectories following loss of RNA interference in Cryptococcus neoformans., Proc Natl Acad Sci U S A, vol. 121 no. 47 (November, 2024), pp. e2416656121 [doi]  [abs]
3. Huang, J; Larmore, CJ; Priest, SJ; Xu, Z; Dietrich, FS; Yadav, V; Magwene, PM; Sun, S; Heitman, J, Distinct evolutionary trajectories following loss of RNA interference in Cryptococcus neoformans. (October, 2024) [doi]
4. Sauters, TJC; Roth, C; Murray, D; Sun, S; Floyd Averette, A; Onyishi, CU; May, RC; Heitman, J; Magwene, PM, Amoeba predation of Cryptococcus: A quantitative and population genomic evaluation of the accidental pathogen hypothesis., PLoS Pathog, vol. 19 no. 11 (November, 2023), pp. e1011763 [doi]  [abs]
5. Vijayraghavan, S; Kozmin, SG; Strope, PK; Skelly, DA; Magwene, PM; Dietrich, FS; McCusker, JH, RNA viruses, M satellites, chromosomal killer genes, and killer/nonkiller phenotypes in the 100-genomes S. cerevisiae strains., G3 (Bethesda), vol. 13 no. 10 (September, 2023) [doi]  [abs]