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Paul M. Magwene, Associate Professor of Biology and Molecular Genetics and Microbiology and Director of the PhD Program in Computational Biology and Bioinformatics


Paul M. Magwene

Contact Info:
Office Location:  124 Science Drive, Room 4103 Ffsc, Duke Box 90338, Durham, NC 27708
Office Phone:  (919) 613-8159
Email Address: send me a message
Web Pages:

Teaching (Fall 2018):

    French Sci 4233, TuTh 04:40 PM-05:55 PM
  • CBB 510S.01, COMP BIO SEMINAR Synopsis
    French Sci 4233, M 11:45 AM-12:30 PM


Ph.D.University of Chicago1999
ABHarvard College1993



Research Interests: Evolutionary Genomics and Bioinformatics


Adaptation, Biological • Biofilms • bioinformatics • Biological Evolution • Computational Biology • Cyclic AMP-Dependent Protein Kinases • evolution • Evolution, Molecular • Genetic Association Studies • Genetic Variation • genetics • Genome, Fungal • genomics • Genomics • Genotype • Models, Biological • Models, Statistical • Multivariate Analysis • networks • Quantitative Trait Loci • theory

Current Ph.D. Students   (Former Students)

Postdocs Mentored
  • Daniel Skelly (2013 - present)  
  • Helen Murphy (2013 - 2014)  
  • Jennifer Reininga-Craven (2009 - 2011)  
  • Josh Granek (2007 - 2012)  

Recent Publications   (More Publications)

  1. Roth, C; Sun, S; Billmyre, RB; Heitman, J; Magwene, PM, A High Resolution Map of Meiotic Recombination in Cryptococcus deneoformans Demonstrates Decreased Recombination in Unisexual Reproduction., Genetics (April, 2018) [doi]  [abs]
  2. Ehrenreich, IM; Magwene, PM, Genetic Dissection of Heritable Traits in Yeast Using Bulk Segregant Analysis., Cold Spring Harbor protocols, vol. 2017 no. 6 (June, 2017), pp. pdb.prot088989 [doi]  [abs]
  3. Ehrenreich, IM; Magwene, PM, Genetic Analysis of Complex Traits in Saccharomyces cerevisiae., Cold Spring Harbor protocols, vol. 2017 no. 6 (June, 2017), pp. pdb.top077602 [doi]  [abs]
  4. Maxwell, CS; Magwene, PM, When sensing is gambling: An experimental system reveals how plasticity can generate tunable bet-hedging strategies., Evolution, vol. 71 no. 4 (April, 2017), pp. 859-871 [doi]  [abs]
  5. Skelly, DA; Magwene, PM; Meeks, B; Murphy, HA, Known mutator alleles do not markedly increase mutation rate in clinical Saccharomyces cerevisiae strains., Proceedings of the Royal Society of London: Biological Sciences, vol. 284 no. 1852 (April, 2017) [doi]  [abs]