Publications [#283975] of Piotr E. Marszalek

Papers Published

1. Zhang, Q; Marszalek, PE, Identification of sugar isomers by single-molecule force spectroscopy., Journal of the American Chemical Society, vol. 128 no. 17 (May, 2006), pp. 5596-5597, ISSN 0002-7863 [16637601], [doi]
   (last updated on 2023/06/01)

   Abstract:
   The nanomechanical properties of beta-galactan, a 1 --> 4 linked beta-d-galactose polysaccharide, were investigated with AFM-based single-molecule force spectroscopy. AFM captured a unique plateau at 640 pN in the force spectrogram of beta-galactan, which is significantly different than the plateau at 280 pN in the force spectrogram of amylose. Thus, our results demonstrate that force spectroscopy is able to discriminate between sugar isomers in which axial and equatorial bonds at C1 and C4 are swapped.