Math @ Duke
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Publications [#287294] of Harold Layton
Papers Published
- Layton, HE; Pitman, EB, A dynamic numerical method for models of renal tubules.,
Bulletin of Mathematical Biology, vol. 56 no. 3
(May, 1994),
pp. 547-565, ISSN 0092-8240 [doi]
(last updated on 2022/08/06)
Abstract: We show that an explicit method for solving hyperbolic partial differential equations can be applied to a model of a renal tubule to obtain both dynamic and steady-state solutions. Appropriate implementation of this method eliminates numerical instability arising from reversal of intratubular flow direction. To obtain second-order convergence in space and time, we employ the recently developed ENO (Essentially Non-Oscillatory) methodology. We present examples of computed flows and concentration profiles in representative model contexts. Finally, we indicate briefly how model tubules may be coupled to construct large-scale simulations of the renal counterflow system.
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