Jichun Xie, Associate Professor of Biostatistics & Bioinformatics

Contact Info:

Office Location:	Hock Plaza 10048, 2424 Erwin Rd, Durham, NC 27705, Durham, NC 27705
Office Phone:	(919) 684-6465
Email Address:

Teaching (Fall 2023):

• BIOSTAT 906.01, STATISTICAL INFERENCE Synopsis

  Hock Plaza 11025, MW 10:05 AM-11:20 AM

Education:

Ph.D.

University of Pennsylvania

2011

Recent Publications   (More Publications)

1. Pura, JA; Li, X; Chan, C; Xie, J, TEAM: A MULTIPLE TESTING ALGORITHM ON THE AGGREGATION TREE FOR FLOW CYTOMETRY ANALYSIS, The Annals of Applied Statistics, vol. 17 no. 1 (March, 2023), pp. 621-640 [doi]  [abs]
2. Fang, J; Chan, C; Owzar, K; Wang, L; Qin, D; Li, Q-J; Xie, J, Clustering Deviation Index (CDI): a robust and accurate internal measure for evaluating scRNA-seq data clustering., Genome Biology, vol. 23 no. 1 (December, 2022), pp. 269 [doi]  [abs]
3. Murdoch, DM; Barfield, R; Chan, C; Towe, SL; Bell, RP; Volkheimer, A; Choe, J; Hall, SA; Berger, M; Xie, J; Meade, CS, Neuroimaging and immunological features of neurocognitive function related to substance use in people with HIV., J Neurovirol (November, 2022) [doi]  [abs]
4. DiMarco, AV; Qin, X; McKinney, BJ; Garcia, NMG; Van Alsten, SC; Mendes, EA; Force, J; Hanks, BA; Troester, MA; Owzar, K; Xie, J; Alvarez, JV, APOBEC Mutagenesis Inhibits Breast Cancer Growth through Induction of T cell-Mediated Antitumor Immune Responses., Cancer Immunol Res, vol. 10 no. 1 (January, 2022), pp. 70-86 [doi]  [abs]
5. Siamakpour-Reihani, S; Cao, F; Lyu, J; Ren, Y; Nixon, AB; Xie, J; Bush, AT; Starr, MD; Bain, JR; Muehlbauer, MJ; Ilkayeva, O; Byers Kraus, V; Huebner, JL; Chao, NJ; Sung, AD, Evaluating immune response and metabolic related biomarkers pre-allogenic hematopoietic stem cell transplant in acute myeloid leukemia., Plos One, vol. 17 no. 6 (2022), pp. e0268963 [doi]  [abs]

Recent Grant Support

• New computational methods to dynamically pinpointing the subregions carrying disease-associated rare variants, National Institutes of Health, 2022/09-2026/07.      
• Race-related differential RNA splicing: novel targets for precision oncology in non-small cell lung cancer, National Institutes of Health, 2020/09-2025/11.      
• Training Program in Bioinformatics at the Intersection of Cancer Immunology and Microbiome, National Institutes of Health, 2020/07-2025/06.      
• Bioinformatics and Computational Biology Training Program, National Institutes of Health, 2005/07-2021/08.      
• Identification and validation of plasma-based protein biomarkers for cediranib and olaparib, Leidos Biomedical Research, Inc., 2019/09-2020/08.      
• A hands-on, integrative next-generation sequencing course: design, experiment, and analysis, National Institutes of Health, 2016/09-2020/06.      
• Statistical/Computational Methods for Pharmacogenomics and Individualized Therapy, University of North Carolina - Chapel Hill, 2015/05-2020/03.