Psychology and Neuroscience Faculty Database
Psychology and Neuroscience
Arts & Sciences
Duke University

 HOME > Arts & Sciences > pn > Faculty    Search Help Login pdf version printable version 

Publications [#252062] of Ahmad Hariri

search PubMed.

Journal Articles

  1. Hariri, AR; Holmes, A (2006). Genetics of emotional regulation: the role of the serotonin transporter in neural function. Trends in Cognitive Sciences, 10(4), 182-191. [16530463], [doi]
    (last updated on 2017/11/20)

    Abstract:
    Identifying biological mechanisms through which genes lead to individual differences in emotional behavior is paramount to our understanding of how such differences confer risk for neuropsychiatric illness. The emergence of techniques such as in vivo imaging of brain function in humans and genetic engineering in rodents has provided important new insights into the impact of serotonin (5-HT), a key modulator of emotional behavior, on neural systems subserving anxiety and depression. A major finding has been the discovery of genetic variation in a crucial regulatory molecule within the 5-HT system, the 5HT transporter (5-HTT), and its influence on emotional traits. The study of the 5-HTT provides a new foundation for understanding the neurobiological and genetic basis of emotional regulation and affective illness.


Duke University * Arts & Sciences * Faculty * Staff * Grad * Postdocs * Reload * Login