Publications [#364180] of Ahmad Hariri

Journal Articles

1. Kim, MJ; Elliott, ML; Knodt, AR; Hariri, AR (2022). A Connectome-wide Functional Signature of Trait Anger.. Clinical psychological science : a journal of the Association for Psychological Science, 10(3), 584-592. [doi]
   (last updated on 2024/04/19)

   Abstract:
   Past research on the brain correlates of trait anger has been limited by small sample sizes, a focus on relatively few regions-of-interest, and poor test-retest reliability of functional brain measures. To address these limitations, we conducted a data-driven analysis of variability in connectome-wide functional connectivity in a sample of 1,048 young adult volunteers. Multi-dimensional matrix regression analysis showed that self-reported trait anger maps onto variability in the whole-brain functional connectivity patterns of three brain regions that serve action-related functions: bilateral supplementary motor area (SMA) and the right lateral frontal pole. We then demonstrate trait anger modulates the functional connectivity of these regions with canonical brain networks supporting somatomotor, affective, self-referential, and visual information processes. Our findings offer novel neuroimaging evidence for interpreting trait anger as a greater propensity to provoked action, supporting ongoing efforts to understand its utility as a potential transdiagnostic marker for disordered states characterized by aggressive behavior.