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Publications [#251232] of Avshalom Caspi

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Journal Articles

  1. Shearer, DM; Thomson, WM; Caspi, A; Moffitt, TE; Broadbent, JM; Poulton, R (2011). Inter-generational continuity in periodontal health: findings from the Dunedin family history study.. Journal of Clinical Periodontology, 38(4), 301-309. [21281332], [doi]
    (last updated on 2018/04/24)

    Abstract:
    OBJECTIVE: To determine whether parental periodontal disease history is a risk factor for periodontal disease in adult offspring. METHODS: Proband periodontal examination [combined attachment loss (CAL) at age 32, and incidence of CAL from ages 26 to 32] and interview data were collected during the age-32 assessments in the Dunedin Study. Parental data were also collected. The sample was divided into two familial-risk groups for periodontal disease (high- and low-risk) based on parents' self-reported periodontal disease. RESULTS: Periodontal risk analysis involved 625 proband-parent(s) groups. After controlling for confounding factors, the high-familial-risk periodontal group was more likely to have 1+ sites with 4+mm CAL [relative risk (RR) 1.45; 95% confidence interval (CI) 1.11-1.88], 2+ sites with 4+mm CAL (RR 1.45; 95% CI 1.03-2.05), 1+ sites with 5+mm CAL (RR 1.60; 95% CI 1.02-2.50), and 1+ sites with 3+mm incident CAL (RR 1.64; 95% CI 1.01-2.66) than the low-familial-risk group. Predictive validity was enhanced when information was available from both parents. CONCLUSIONS: Parents with poor periodontal health tend to have offspring with poor periodontal health. Family/parental history of oral health is a valid representation of the shared genetic and environmental factors that contribute to an individual's periodontal status, and may help to predict patient prognosis and preventive treatment need.


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