Amir H. Rezvani, Professor in Psychiatry and Behavioral Sciences and Psychology and Neuroscience and Faculty Network Member of Duke Institute for Brain Sciences and Affiliate of the Duke Initiative for Science & Society

Amir H. Rezvani
Contact Info:
Office Location:  323 Foster St., Durham, NC 27701
Office Phone:  (919) 668-1880
Email Address:   send me a message
Web Page:   http://faculty.duhs.duke.edu/faculty/info?pid=5055

Office Hours:

By appointment.
Education:

Ph.D.University of Illinois -- Urbana-Champaign1983
Representative Publications   (More Publications)   (search)

  1. Rezvani, AH; Cauley, M; Xiao, Y; Kellar, KJ; Levin, ED (2013). Effects of chronic sazetidine-A, a selective α4β2 neuronal nicotinic acetylcholine receptors desensitizing agent on pharmacologically- induced impaired attention in rats. Psychopharmacology, 226(1), 35-43. [23100170], [doi]  [abs]
  2. Levin, ED; Cauley, M; Rezvani, AH (2013). Improvement of attentional function with antagonism of nicotinic receptors in female rats.. European Journal of Pharmacology, 702(1-3), 269-274. [23399762], [doi]  [abs]
  3. Hussmann, GP; Turner, JR; Lomazzo, E; Venkatesh, R; Cousins, V; Xiao, Y; Yasuda, RP; Wolfe, BB; Perry, DC; Rezvani, AH; Levin, ED; Blendy, JA; Kellar, KJ (2012). Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain.. The Journal of pharmacology and experimental therapeutics, 343(2), 441-450. [22899752], [doi]  [abs]
  4. Rezvani, AH; Cauley, MC; Johnson, EC; Gatto, GJ; Levin, ED (2012). Effects of AZD3480, a neuronal nicotinic acetylcholine receptor agonist, and donepezil on dizocilpine-induced attentional impairment in rats.. Psychopharmacology, 223(3), 251-258. [22526540], [doi]  [abs]
  5. Swartzwelder, NA; Risher, ML; Abdelwahab, SH; D'Abo, A; Rezvani, AH; Levin, ED; Wilson, WA; Swartzwelder, HS; Acheson, SK (2012). Effects of ethanol, Δ(9)-tetrahydrocannabinol, or their combination on object recognition memory and object preference in adolescent and adult male rats.. Neuroscience Letters, 527(1), 11-15. [22959891], [doi]  [abs]
  6. Rezvani, AH; Lawrence, AJ; Arolfo, MP; Levin, ED; Overstreet, DH (2012). Novel medication targets for the treatment of alcoholism: preclinical studies.. Recent Patents on CNS Drug Discovery, 7(2), 151-162. [22574676]  [abs]
  7. Johnson, JE; Slade, S; Wells, C; Petro, A; Sexton, H; Rezvani, AH; Brown, ML; Paige, MA; McDowell, BE; Xiao, Y; Kellar, KJ; Levin, ED (2012). Assessing the effects of chronic sazetidine-A delivery on nicotine self-administration in both male and female rats.. Psychopharmacology, 222(2), 269-276. [22297831], [doi]  [abs]
  8. Bartley, PC; Rezvani, AH (2012). Alcohol and cognition - consideration of age of initiation, usage patterns and gender: a brief review.. Current Drug Abuse Reviews, 5(2), 87-97. [22455507]  [abs]
  9. Rezvani, AH; Timofeeva, O; Sexton, HG; DeCuir, D; Xiao, Y; Gordon, CJ; Kellar, KJ; Levin, ED (2012). Effects of sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats.. European Journal of Pharmacology, 682(1-3), 110-117. [22387853], [doi]  [abs]
  10. Levin, ED; Slade, S; Wells, C; Cauley, M; Petro, A; Vendittelli, A; Johnson, M; Williams, P; Horton, K; Rezvani, AH (2011). Threshold of adulthood for the onset of nicotine self-administration in male and female rats.. Behavioural Brain Research, 225(2), 473-481. [21854810], [doi]  [abs]
  11. Cippitelli, A; Rezvani, AH; Robinson, JE; Eisenberg, L; Levin, ED; Bonaventure, P; Motley, ST; Lovenberg, TW; Heilig, M; Thorsell, A (2011). The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety.. Alcohol, 45(6), 567-576. [21145691], [doi]  [abs]
  12. Levin, ED; Bushnell, PJ; Rezvani, AH (2011). Attention-modulating effects of cognitive enhancers.. Pharmacology, Biochemistry and Behavior, 99(2), 146-154. [21334367], [doi]  [abs]
  13. Rezvani, AH; Cauley, M; Sexton, H; Xiao, Y; Brown, ML; Paige, MA; McDowell, BE; Kellar, KJ; Levin, ED (2011). Sazetidine-A, a selective α4β2 nicotinic acetylcholine receptor ligand: effects on dizocilpine and scopolamine-induced attentional impairments in female Sprague-Dawley rats.. Psychopharmacology, 215(4), 621-630. [21274704], [doi]  [abs]
  14. Galici, R; Rezvani, AH; Aluisio, L; Lord, B; Levin, ED; Fraser, I; Boggs, J; Welty, N; Shoblock, JR; Motley, ST; Letavic, MA; Carruthers, NI; Dugovic, C; Lovenberg, TW; Bonaventure, P (2011). JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.. Psychopharmacology, 214(4), 829-841. [21086115], [doi]  [abs]
  15. Rezvani, AH; Slade, S; Wells, C; Petro, A; Lumeng, L; Li, T-K; Xiao, Y; Brown, ML; Paige, MA; McDowell, BE; Rose, JE; Kellar, KJ; Levin, ED (2010). Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats.. Psychopharmacology, 211(2), 161-174. [20535453], [doi]  [abs]
  16. AH Rezvani, H Sexton, ED Levin (2010). Persistent high alcohol consumption in alcohol-preferring (P) rats results from a lack of normal aversion to alcohol.. Alcohol and alcoholism (Oxford, Oxfordshire), 45(3), 219-22. [doi]  [abs]
  17. Levin, ED; Rezvani, AH; Xiao, Y; Slade, S; Cauley, M; Wells, C; Hampton, D; Petro, A; Rose, JE; Brown, ML; Paige, MA; McDowell, BE; Kellar, KJ (2010). Sazetidine-A, a selective alpha4beta2 nicotinic receptor desensitizing agent and partial agonist, reduces nicotine self-administration in rats.. The Journal of pharmacology and experimental therapeutics, 332(3), 933-939. [20007754], [doi]  [abs]
  18. Rezvani, AH; Overstreet, DH; Vaidya, AH; Zhao, B; Levin, ED (2009). Carisbamate, a novel antiepileptic candidate compound, attenuates alcohol intake in alcohol-preferring rats.. Alcoholism: Clinical and Experimental Research, 33(8), 1366-1373. [19413647], [doi]  [abs]
  19. Tizabi, Y; Getachew, B; Rezvani, AH; Hauser, SR; Overstreet, DH (2009). Antidepressant-like effects of nicotine and reduced nicotinic receptor binding in the Fawn-Hooded rat, an animal model of co-morbid depression and alcoholism.. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 33(3), 398-402. [18835320], [doi]  [abs]
  20. Rezvani, AH; Kholdebarin, E; Cauley, MC; Dawson, E; Levin, ED (2009). Attenuation of pharmacologically-induced attentional impairment by methylphenidate in rats.. Pharmacology Biochemistry and Behavior, 92(1), 141-146. [19041337], [doi]  [abs]
  21. Rezvani, AH; Kholdebarin, E; Brucato, FH; Callahan, PM; Lowe, DA; Levin, ED (2009). Effect of R3487/MEM3454, a novel nicotinic alpha7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats.. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 33(2), 269-275. [19110025], [doi]  [abs]
  22. Levin, ED; Petro, A; Rezvani, AH; Pollard, N; Christopher, NC; Strauss, M; Avery, J; Nicholson, J; Rose, JE (2009). Nicotinic alpha7- or beta2-containing receptor knockout: effects on radial-arm maze learning and long-term nicotine consumption in mice.. Behavioural Brain Research, 196(2), 207-213. [18831991], [doi]  [abs]
  23. Levin, ED; Slade, S; Johnson, M; Petro, A; Horton, K; Williams, P; Rezvani, AH; Rose, JE (2008). Ketanserin, a 5-HT2 receptor antagonist, decreases nicotine self-administration in rats.. European Journal of Pharmacology, 600(1-3), 93-97. [18950618], [doi]  [abs]
  24. Rezvani, AH; Eddins, D; Slade, S; Hampton, DS; Christopher, NC; Petro, A; Horton, K; Johnson, M; Levin, ED (2008). Neonatal 6-hydroxydopamine lesions of the frontal cortex in rats: persisting effects on locomotor activity, learning and nicotine self-administration.. Neuroscience, 154(3), 885-897. [18511204], [doi]  [abs]
  25. Rezvani, AH; Tizabi, Y; Getachew, B; Hauser, SR; Caldwell, DP; Hunter, C; Levin, ED (2008). Chronic nicotine and dizocilpine effects on nicotinic and NMDA glutamatergic receptor regulation: interactions with clozapine actions and attentional performance in rats.. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 32(4), 1030-1040. [18343006], [doi]  [abs]
  26. Schramm-Sapyta, NL; Kingsley, MA; Rezvani, AH; Propst, K; Swartzwelder, HS; Kuhn, CM (2008). Early ethanol consumption predicts relapse-like behavior in adolescent male rats.. Alcoholism: Clinical and Experimental Research, 32(5), 754-762. [18336637], [doi]  [abs]
  27. Rezvani, AH; Kholdebarin, E; Dawson, E; Levin, ED (2008). Nicotine and clozapine effects on attentional performance impaired by the NMDA antagonist dizocilpine in female rats.. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), 11(1), 63-70. [17295931], [doi]  [abs]
  28. Levin, ED; Rezvani, AH (2007). Nicotinic interactions with antipsychotic drugs, models of schizophrenia and impacts on cognitive function.. Biochemical Pharmacology, 74(8), 1182-1191. [17714691], [doi]  [abs]
  29. Rezvani, AH; Overstreet, DH; Cleves, M; Parsian, A (2007). Further genetic characterization of the fawn-hooded (FH/Wjd) rat, an animal model of comorbid depression and alcoholism.. Psychiatric Genetics, 17(2), 77-83. [17413446], [doi]  [abs]
  30. ED Levin, SS Lawrence, A Petro, K Horton, AH Rezvani, FJ Seidler, TA Slotkin (2007). Adolescent vs. adult-onset nicotine self-administration in male rats: duration of effect and differential nicotinic receptor correlates.. Neurotoxicology and teratology, 29(4), 458-65. [doi]  [abs]
  31. Patra, B; Overstreet, DH; Rezvani, AH; Cleves, M; Parsian, A (2007). Analysis of alcohol-related phenotypes in F2 progeny derived from FH/Wjd and ACI/N rat strains reveals independent measures and sex differences.. Behavioural Brain Research, 177(1), 37-44. [17161877], [doi]  [abs]
  32. Rezvani, AH; Overstreet, DH; Levin, ED; Rosenthal, DI; Kordik, CP; Reitz, AB; Vaidya, AH (2007). Effects of atypical anxiolytic N-phenyl-2-[1-[3-(2-pyridinylethynyl)benzoyl]-4-piperidine]acetamide (JNJ-5234801) on alcohol intake in alcohol-preferring P rats.. Alcoholism: Clinical and Experimental Research, 31(1), 57-63. [17207102], [doi]  [abs]
  33. Overstreet, DH; Rezvani, AH; Djouma, E; Parsian, A; Lawrence, AJ (2007). Depressive-like behavior and high alcohol drinking co-occur in the FH/WJD rat but appear to be under independent genetic control.. Neuroscience & Biobehavioral Reviews, 31(1), 103-114. [16982094], [doi]  [abs]
  34. Overstreet, DH; Rezvani, AH; Cowen, M; Chen, F; Lawrence, AJ (2006). Modulation of high alcohol drinking in the inbred Fawn-Hooded (FH/Wjd) rat strain: implications for treatment.. Addiction Biology, 11(3-4), 356-373. [16961764], [doi]  [abs]
  35. AH Rezvani, DP Caldwell, ED Levin (2006). Chronic nicotine interactions with clozapine and risperidone and attentional function in rats.. Progress in neuro-psychopharmacology & biological psychiatry, 30(2), 190-7. [doi]  [abs]
  36. Rezvani, AH; Caldwell, DP; Levin, ED (2006). Chronic nicotine interactions with clozapine and risperidone and attentional function in rats.. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 30(2), 190-197. [16310917], [doi]  [abs]
  37. Levin, ED; McClernon, FJ; Rezvani, AH (2006). Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization.. Psychopharmacology, 184(3-4), 523-539. [16220335], [doi]  [abs]
  38. Levin, ED; Rezvani, AH (2006). Nicotinic-antipsychotic drug interactions and cognitive function.. EXS, 98, 185-205. [17019889]  [abs]
  39. Barron, S; White, A; Swartzwelder, HS; Bell, RL; Rodd, ZA; Slawecki, CJ; Ehlers, CL; Levin, ED; Rezvani, AH; Spear, LP (2005). Adolescent vulnerabilities to chronic alcohol or nicotine exposure: findings from rodent models.. Alcoholism: Clinical and Experimental Research, 29(9), 1720-1725. [16205372]  [abs]
  40. Rezvani, AH; Caldwell, DP; Levin, ED (2005). Nicotinic-serotonergic drug interactions and attentional performance in rats.. Psychopharmacology, 179(3), 521-528. [15682310], [doi]  [abs]
  41. Levin, ED; Tizabi, Y; Rezvani, AH; Caldwell, DP; Petro, A; Getachew, B (2005). Chronic nicotine and dizocilpine effects on regionally specific nicotinic and NMDA glutamate receptor binding.. Brain Research, 1041(2), 132-142. [15829222], [doi]  [abs]
  42. Rezvani, AH; Levin, ED (2004). Adolescent and adult rats respond differently to nicotine and alcohol: motor activity and body temperature.. International Journal of Developmental Neuroscience, 22(5-6), 349-354. [15380834], [doi]  [abs]
  43. Rezvani, AH; Levin, ED (2004). Nicotine-antipsychotic drug interactions and attentional performance in female rats.. European Journal of Pharmacology, 486(2), 175-182. [14975706], [doi]  [abs]
  44. Levin, ED; Rezvani, AH; Montoya, D; Rose, JE; Swartzwelder, HS (2003). Adolescent-onset nicotine self-administration modeled in female rats.. Psychopharmacology, 169(2), 141-149. [12764575], [doi]  [abs]
  45. Rezvani, AH; Levin, ED (2003). Nicotine-alcohol interactions and attentional performance on an operant visual signal detection task in female rats.. Pharmacology Biochemistry and Behavior, 76(1), 75-83. [13679219]  [abs]
  46. Rezvani, AH; Overstreet, DH; Perfumi, M; Massi, M (2003). Plant derivatives in the treatment of alcohol dependency.. Pharmacology Biochemistry and Behavior, 75(3), 593-606. [12895677]  [abs]
  47. Rezvani, AH; Levin, ED (2003). Nicotinic-glutamatergic interactions and attentional performance on an operant visual signal detection task in female rats.. European Journal of Pharmacology, 465(1-2), 83-90. [12650836]  [abs]
  48. Chen, F; Rezvani, AH; Lawrence, AJ (2003). Autoradiographic quantification of neurochemical markers of serotonin, dopamine and opioid systems in rat brain mesolimbic regions following chronic St John's wort treatment.. Naunyn-Schmiedeberg's Archives of Pharmacology, 367(2), 126-133. [12595953], [doi]  [abs]
  49. Overstreet, DH; Keung, W-M; Rezvani, AH; Massi, M; Lee, DYW (2003). Herbal remedies for alcoholism: promises and possible pitfalls.. Alcoholism: Clinical and Experimental Research, 27(2), 177-185. [12605067], [doi]  [abs]
  50. Rezvani, AH; Bushnell, PJ; Levin, ED (2002). Effects of nicotine and mecamylamine on choice accuracy in an operant visual signal detection task in female rats.. Psychopharmacology, 164(4), 369-375. [12457266], [doi]  [abs]
  51. Levin, ED; Rezvani, AH (2002). Nicotinic treatment for cognitive dysfunction.. Current drug targets. CNS and neurological disorders, 1(4), 423-431. [12769614]  [abs]
  52. Rezvani, AH; Levin, ED (2002). Nicotine-alcohol interactions and cognitive function in rats.. Pharmacology Biochemistry and Behavior, 72(4), 865-872. [12062576]  [abs]
  53. AH Rezvani, PJ Bushnell, JM Burkholder, HB Glasgow Jr, ED Levin (2002). Specificity of cognitive impairment from Pfiesteria piscicida exposure in rats: attention and visual function versus behavioral plasticity.. Neurotoxicology and teratology, 23(6), 609-16.  [abs]
  54. Rezvani, AH; Parsian, A; Overstreet, DH (2002). The Fawn-Hooded (FH/Wjd) rat: a genetic animal model of comorbid depression and alcoholism.. Psychiatric Genetics, 12(1), 1-16. [11901354]  [abs]
  55. Gordon, CJ; Rezvani, AH (2001). Genetic selection of rats with high and low body temperatures.. Journal of Thermal Biology, 26(3), 223-229. [11240229]  [abs]
  56. Rezvani, AH; Levin, ED (2001). Cognitive effects of nicotine.. Biological Psychiatry, 49(3), 258-267. [11230877]  [abs]
  57. 1. Rezvani A.H., and Levin E.D. Cognitive effects of nicotine. Biological Psychiatry 49: 258-267, 2001..
  58. 2. Matthews D.B., Overstreet D.H. Rezvani A.H., Devaud L.L., and Morrow A.L. Effects of sweetened ethanol solutions on ethanol self-administration and blood ethanol levels. Pharmacol. Biochem. Behav. 68:13-21, 2001..
  59. 3. Gordon C.J., and Rezvani A.H. Genetic selection of rats with high and low body temperatures. J. Thermal Biology 26:23-29, 2001..
  60. 4. Rezvani AH, Bushnell PJ, Burkholder JM, Glasgow HB, and Levin ED. Specificity of cognitive impairment from Pfiesteria piscicida exposure in rats: Attention and visual function vs behavioral plasticity. Neurotoxicology and Teratology 23:609-616 2001..
  61. 6. Levin ED, Rezvani AH. Nicotine involvement in memory function of rats. In: Nicotinic receptors in the nervous system Levin E.D. ed. Pp167-178, CRC Press, 2001..
  62. Levin, ED; Mead, T; Rezvani, AH; Rose, JE; Gallivan, C; Gross, R (2000). The nicotinic antagonist mecamylamine preferentially inhibits cocaine vs. food self-administration in rats.. Physiology & Behavior, 71(5), 565-570. [11239676]  [abs]
  63. ED Levin, AH Rezvani, NC Christopher, HB Glasgow Jr, NJ Deamer-Melia, JM Burkholder, VC Moser, K Jensen (2000). Rapid neurobehavioral analysis of Pfiesteria piscicida effects in juvenile and adult rats.. Neurotoxicology and teratology, 22(4), 533-40.  [abs]
  64. Levin, ED; Rezvani, AH (2000). Development of nicotinic drug therapy for cognitive disorders.. European Journal of Pharmacology, 393(1-3), 141-146. [10771007]  [abs]
  65. Farren, CK; Rezvani, AH; Overstreet, D; O'Malley, S (2000). Combination pharmacotherapy in alcoholism: a novel treatment approach.. CNS spectrums, 5(2), 70-76. [18297000]  [abs]
  66. Rezvani, AH; Overstreet, DH; Mason, GA; Janowsky, DS; Hamedi, M; Clark, E; Yang, Y (2000). Combination pharmacotherapy: a mixture of small doses of naltrexone, fluoxetine, and a thyrotropin-releasing hormone analogue reduces alcohol intake in three strains of alcohol-preferring rats.. Alcohol and Alcoholism, 35(1), 76-83. [10684782]  [abs]
  67. AH Rezvani, DH Overstreet, Y Yang, E Clark Jr (1999). Attenuation of alcohol intake by extract of Hypericum perforatum (St. John's Wort) in two different strains of alcohol-preferring rats.. Alcohol and alcoholism (Oxford, Oxfordshire), 34(5), 699-705.  [abs]
  68. Overstreet, DH; Kampov-Polevoy, AB; Rezvani, AH; Braun, C; Bartus, RT; Crews, FT (1999). Suppression of alcohol intake by chronic naloxone treatment in P rats: tolerance development and elevation of opiate receptor binding.. Alcoholism: Clinical and Experimental Research, 23(11), 1761-1771. [10591592]  [abs]
  69. DH Overstreet, AH Rezvani, A Parsian (1999). Behavioural features of alcohol-preferring rats: focus on inbred strains.. Alcohol and alcoholism (Oxford, Oxfordshire), 34(3), 378-85.  [abs]
  70. Cowen, MS; Rezvani, AH; Jarrott, B; Lawrence, AJ (1999). Ethanol consumption by Fawn-Hooded rats following abstinence: effect of naltrexone and changes in mu-opioid receptor density.. Alcoholism: Clinical and Experimental Research, 23(6), 1008-1014. [10397284]  [abs]
  71. Tizabi, Y; Overstreet, DH; Rezvani, AH; Louis, VA; Clark, E; Janowsky, DS; Kling, MA (1999). Antidepressant effects of nicotine in an animal model of depression.. Psychopharmacology, 142(2), 193-199. [10102772]  [abs]