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Publications [#275610] of Amir H. Rezvani

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Papers Published

  1. Rezvani, AH; Grady, DR; Janowsky, DS (1991). Effect of calcium-channel blockers on alcohol consumption in alcohol-drinking monkeys.. Alcohol and Alcoholism (Oxford, Oxfordshire), 26(2), 161-167. [1652252]
    (last updated on 2019/02/20)

    Abstract:
    Experiments were performed to determine the effect of the calcium-channel blockers verapamil and diltiazem on ethanol preference in monkeys. Two days of administration of 10 mg/kg verapamil but not diltiazem or saline significantly decreased ethanol intake in all monkeys tested. Chronic treatment with verapamil, but not saline, dose-dependently attenuated alcohol intake, without significantly influencing water intake. These findings suggest that verapamil exerts an inhibitory action on ethanol preference in chronically alcohol-drinking monkeys, possibly by interfering with Ca(2+)-channels and/or by interacting with the activity of certain central neurotransmitters.


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