Publications [#271874] of Michael D. De Bellis

Journal Articles

1. Diwadkar, VA; DeBellis, MD; Sweeney, JA; Pettegrew, JW; Keshavan, MS (2004). Abnormalities in MRI-measured signal intensity in the corpus callosum in schizophrenia.. Schizophrenia Research, 67(2-3), 277-282. [doi]
   (last updated on 2022/08/06)

   Abstract:
   The microstructural integrity of the corpus callosum (CC) in first-episode schizophrenia patients was assessed by measuring the signal intensity (SI) in T1-weighted MRI images. Analyses revealed that compared to both healthy controls and non-schizophrenic patients, schizophrenia patients showed reductions in SI in all the callosal subregions, the genu, body, isthmus and splenium in first-episode schizophrenia. These results indicate that schizophrenia is characterized by pathology of this principal interhemispheric commissure; the abnormalities may reflect distributed (rather than localized) interhemispheric disconnectivity that extends beyond the heteromodal association cortices.