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Publications [#274420] of Edward D. Levin

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Papers Published

  1. Levin, ED; Bowman, RE (1988). Long-term effects of chronic postnatal lead exposure on delayed spatial alternation in monkeys.. Neurotoxicology and Teratology, 10(6), 505-510. [3244342], [doi]
    (last updated on 2019/12/11)

    Abstract:
    Two cohorts of monkeys chronically exposed to lead during the first year after birth and their controls were tested during adulthood for choice accuracy on a learning and memory task, delayed spatial alternation (DSA). Neither cohort showed significant lead-related deficits, as had been seen in a previous experiment with monkeys exposed to similar chronic levels of lead during the first year with an additional high pulse given five-six weeks after birth (18,19). On the contrary, the lead-exposed monkeys in the present experiment actually performed slightly better than controls. In the previous (pulse-chronic) study, the deficit occurred at short intertrial delays, suggesting an attentional rather than mnenomic deficit. A lead-induced decrease in attentiveness could also explain the present results. The lower level lead intoxication may have decreased attentiveness to a lesser degree, so that the monkeys were less susceptible to irrelevant stimuli and performed better.


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