| Publications [#274513] of Edward D. Levin
search .Papers Published
- Andersson, U; Häggström, JE; Levin, ED; Bondesson, U; Valverius, M; Gunne, LM (1989). Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia.. Mov Disord, 4(1), 37-46. [2927401], [doi]
(last updated on 2024/04/24)
Abstract: Glutamate decarboxylase (GAD) activity was measured in the nuclei of the basal ganglia in patients with neuroleptic-induced tardive dyskinesia (TD) and controls matched for age and premortem state. In five TD patients, who all had a sudden death, a significant decrease in GAD activity was found in the subthalamic nucleus (STN). The lowered GAD activity in the STN may represent a biochemical substrate for neuroleptic-induced TD.
|