Kathleen A Welsh-Bohmer, Associate Professor of Psychiatry and Psychology and Neuroscience

Associate Professor of Psychiatry and Psychology and Neuroscience
Ph.D., University of Virginia,
mailing address: 2200 W Main St Ste A230 Durham, NC 27705
office: 2200 W Main St Ste A230
email:

research interests | publications | lab web site

Representative Publications:

  1. Carlson, M., Tschanz, J., Norton, M., Welsh-Bohmer, K.A., Martin, B., Breitner, J.C.S. (accepted). H2 Histamine receptor blockage in the treatment of Alzheimer's disease: A randomized, double-blind, placebo-controlled trial of nizatidine. Alzheimer's Disease and Associated Disorders..
  2. Welsh-Bohmer, K.A., Gearing, M., Saunders, A.M., Roses, A.D., & Mirra, S.M. (1997). Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Annals of Neurology, 42: 319-325..
  3. Carlson, M.C., Zandi, P.A., Plassman, B.L., Tschanz, J.T., Welsh-Bohmer, K.A. Steffens, D.C., Bastian, L, Mehta, K.M., & Breitner, J.C.S. for the Cache County Study Group (2002). Hormone Replacement Therapy Predicts Improved Cognitive Trajectory In Older Women. The Cache County Study. Neurology, 57: 2210-2216.
  4. Yamaoka, L.H., Welsh-Bohmer, K.A., Hulette, C.M. Gaskell Jr., P.C., Murray, M., Rimmler, J.L., Helms, B.R., Guerra, M., Roses, A.D., Schmechel, D.E., Pericak-Vance, M.A. (1996). Linkage of Frontotemporal dementia to Chromosome 17: Clinical and neuropathological characterization of phenotype. American Journal of Human Genetics, 59, 1306-1312..
  5. Dawson, D.V., Welsh-Bohmer, K.A., & Siegler, I.C. (2001). Informant rated personality change in Alzheimer's disease patients: Replication, influence of premorbid profile, and covariate relationships. Research and Practice in Alzheimer's Disease. Volume 5. In: B. Vellas & J. Fitten (Eds). Auzeville-Tolosane France: Serdi Press, pp 27-32..
  6. Welsh K.A., Hoffman J.M., Earl N.L., & Hansen, M. W. (1994) Neural correlates of dementia: Regional brain metabolism (FDG-PET) and the CERAD neuropsychological battery. Archives of Clinical Neuropsychology, 9, 395-409..
  7. Dawson, D.V., Welsh-Bohmer, K.A., Siegler, I.C. (accepted). Premorbid personality predicts level of rated personality change in AD patients. Alzheimer's Disease and Associated Disorders..
  8. Welsh, K.A., Butters, N., Hughes, J.P., Mohs, R.C., and Heyman, A. (1991) Detection of abnormal memory decline in mild Alzheimer's disease using CERAD neuropsychological measures. Archives of Neurology, 48, 278-281..
  9. Fillenbaum, G.G., Unverzagt, F.W., Ganguli, M., Welsh-Bohmer, K.A. (accepted). The CERAD neuropsychological battery: Performance of representative community and tertiary care samples of African-American and European American elderly. In: F.R. Ferraro (ed). Minority and Cross-Cultural Aspects of Neuropsychological Assessment. London: Swets & Zeitlineger..
  10. Hulette, C.M., Welsh-Bohmer, K.A., Murray, M.G., Mash, D.& McIntyre, L.M. Neuropathological and neuropsychological changes in "normal" aging: Evidence for preclinical Alzheimer's disease. Journal of Neuropathology and Experimental Neurology, 57, 1168-1174..
  11. Grundman, M., Kim, H.T., Salmon, D., Storandt, M., Smith, G., Ferris, S., Mohs, R., Kawas, C., Doody, R., Welsh-Bohmer, K.A.,...Kukull, W., Thal, L.J. for participants in the Alzheimer's Disease Centers' Neuropsychological Database Initiative (2001). The Alzheimer's Disease Centers' Neuropsychological Database Initiative: A Resource for Alzheimer's Disease Prevention Trials. In: K. Iqbal, S.S. Sisodia, and B. Winblad (eds) Alzheimer's disease: Advances in etiology, pathogenesis and therapeutics. The Proceedings of the 7th International conference on Alzheimer's Disease and Related Disorders." London: John Wiley & Son, pp129-140..
  12. Koltai, D.C., Welsh-Bohmer, K.A., & Mason, D.J. (accepted). Neuropsychological consultation and training of family members with dementia. In: G. Prigatano & N. Pliskin (eds). Demonstrating Utility and Cost Effectiveness in Clinical Neuropsychology. Philadelphia: Psychology Press- Taylor & Francis Group..
  13. Koltai, D.C., Welsh-Bohmer, K.A., & Schmechel, D.E. (2001). Influence of anosognosia on treatment outcome among dementia patients. Neuropsychological Rehabilitation, 11: 455-475.
  14. Meich, R.A, Breitner, J.C.S., Zandi, P.P., Khachaturian, A.S., Anthony, J.C., Mayer, L., for the Cache County Study Group. (2002). Incidence of AD may decline in the early 90's for men, later for women: The Cache County Study. Neurology, 58:209-218..
  15. Publications in print.
  16. Schiffman, S.S., Graham, B.G., Sattely-Miller, E.A., Zervakis, J., Welsh-Bohmer, K.A. (in press). Taste, smell, and neuropsychological performance of individuals at risk for Alzheimer's disease. Neurobiology of Aging..
  17. Silverman, D.H.S., Small, G.W., Chang, C.Y., Lu, C.S., Kung de Aburto, M.A., Chen, W., Czernin, J., Rapoport, S.I., Pietrini, P., Alexander, G.E., Schapiro, M.B., Jagust, W.J., Hoffman, J.M., Welsh-Bohmer, K.A., ....& Phelps, M.E. (in press). Neuroimaging in evaluation of dementia: Regional brain metabolism and long-term outcome. Journal of the American Medical Association..
  18. Steffens, D.C., Payne, M.E., Greenberg, D.L., Byrum, C.E., Welsh-Bohmer, K.A., Wagner, H.R., & MacFall, J.R. (accepted). Hippocampal volume and incident dementia in geriatric depression. American Journal of Geriatric Psychiatry..
  19. Sugarman, J., Cain, C., Wallace, R., & Welsh-Bohmer, K.A. (2001). How proxies make decisions about research for patients with Alzheimer's disease. Journal of the American Geriatrics Society, 49, 1110-1119..
  20. Welsh-Bohmer, K.A. & Madden, D.J. (accepted). Benign Senescent Forgetfulness, Age-Associated Memory Impairment, and Age-related cognitive decline. In: J.Copeland, M. Abou-Saleh, & D. Blazer (Eds). Principles and Practice of Geriatric Psychiatry- 2nd Edition. Sussex, England: John Wiley & Sons, Ltd..
  21. Welsh-Bohmer, K.A., Hulette, C., Schmechel, D., Burke, J. & Saunders, A. (2001). Neuropsychological detection of preclinical Alzheimer's disease: Results of a neuropathological series of "normal" controls. In: K. Iqbal, S.S. Sisodia, and B. Winblad (eds) Alzheimer's disease: Advances in etiology, pathogenesis and therapeutics. The Proceedings of the 7th International conference on Alzheimer's Disease and Related Disorders." London: John Wiley & Sons, pp 111-122..
  22. Welsh-Bohmer, K.A., Koltai, D.C., & Mason D.J. (accepted). The clinical utility of neuropsychological evaluation of patients with known or suspected dementia. In: G. Prigatano & N. Pliskin (eds). Demonstrating Utility and Cost Effectiveness in Clinical Neuropsychology. Philadelphia: Psychology Press- Taylor & Francis Group..
  23. Yi-Ju, L., Scott, W.K., Hedges, D.J., Zhang, F., Gaskell, P.C., Nance, M.A., Watts, R.L., Hubble, J.P., Koller, W.C., Pahwa, R., Stern, M.B., Hiner, B.C., Jankovic, J., Allen Jr., F.A., Goetz, C.G., Mastaglia, F., Stajich, J.M., Gibson, R.A., Middleton, L.T., Saunders, A.M., Scott, B.L., Small, G.W., Reed, A.D., Schmechel, D.E., Welsh-Bohmer, K.A., Conneally, P.M., Roses, A.D., Gilbert, J.R., Vance, J.M., Haines, J.L., Pericak-Vance, M.A.. (accepted). Onset in neurodegenerative diseases is genetically controlled. American Journal of Human Genetics..
  24. Koltai, D.C. & Welsh-Bohmer, K.A. (accepted). Geriatric Neuropsychological Assessment. In: R.D. Vanderploeg (Ed) Clinician's Guide to Neuropsychological Assessment, 2nd Edition. New Jersey: Lawrence Erlbaum Associates..
  25. Ogrocki, P.K. & Welsh-Bohmer, K.A. (accepted). Assessment of Cognitive and Functional Impairment in the Elderly. In: C.Clark (Ed) Neurodegenerative Dementia: Clinical Features and Pathological Mechanisms. New York: McGraw Hill..
  26. Welsh-Bohmer, K.A. & Ogrocki, P. K. (1998). Clinical differentiation of memory disorders in neurodegenerative diseases. In: A.I. Troster (Ed), Memory in Neurodegenerative Disease: Biological, Cognitive, and Clinical Perspectives. Cambridge University Press, London, pp 290313..
  27. Davidson M., Harvey P.D., Welsh K.A., Powchik P., Putnam K.M., Mohs R.C. (1996). Defining the dementia of old age schizophrenia: Psychometric comparisons of schizophrenic patients to patients with Alzheimer's disease. American Journal of Psychiatry, 153, 1274-1279..
  28. Fillenbaum, G.G., Peterson, B., Welsh-Bohmer, K.A., Kukull, W., Heyman, A. (accepted) Progression of Alzheimer's disease in African-American and White patients: The CERAD experience, Part XVI. Neurology..
  29. Hoffman, J.M., Hanson, M.W., Welsh, K.A., Earl, N.L., Paine, S., Delong, D. & Coleman, R.E. (1996). Interpretation variability of 18F-fluoro-2-deoxyglucose (FDG) Positron Emission Tomography (PET) studies in dementia. Investigative Radiology, 31, 316-322..
  30. Hulette, C., Welsh-Bohmer, K.A., Crain, B., Szymanski, M.H., Sinclaire, N.O.,& Roses, A.D. (accepted). Rapid brain autopsy. The Bryan Alzheimer's Disease Research Center Experience. Journal of Neuropathology. Plassman, B.L., Welsh-Bohmer, K.A., Bigler, E.D., Johnson, S.C., Anderson, C.V., Helms, M.J., Breitner, J.C.S. (in press). Apolipoprotein E e4 and hippocampal volume in twins with normal cognition. Neurology.
  31. Saunders, A.M., Hulette, C., Welsh-Bohmer, K.A., Schmechel, D.E., Crain, B., Burke, J.R., Alberts, M.A., Strittmatter, W.J., Breitner, J.C.S., Earl, N., Clark, C., Heyman, A., Gaskell, P.C., Pericak-Vance, M.A., & Roses, A.D. (1996). Specificity and sensitivity of apolipoprotein E genotyping in a prospectively ascertained series of probable Alzheimer disease patients with autopsy-confirmed diagnoses. Lancet, 348, 90-93..
  32. Siegler, I., Poon, L., Madden, D., & Welsh, K.A. (1996). Psychological Aspects of Normal Aging. In: E.W. Busse & D.G. Blazer (Eds). Geriatric Psychiatry, 2nd Edition. Washington D.C.: American Psychatric Press, pp 105-127..
  33. Steffens, D.C., Plassman B.L., Helms M.J., Welsh, K.A., Saunders A.M., & Breitner J.C.S. A twin study of late-onset depression and apolipoprotein E e4 as risk factors for Alzheimer's disease. Biological Psychiatry (accepted)..
  34. Steffens, D.C., Welsh, K.A., Burke, J.R., Helms, M.J., Folstein, M.F., Brandt, J., McDonald, W.M., & Breitner, J.C.S. (1996). Diagnosis of Alzheimer's disease in epidemiological studies by staged review of clinical data. Neuropsychiatry, Neuropsychology, and Behavioral Neurology, 9, 107-113..
  35. Welsh-Bohmer, K.A. & Hoffman, J.M. (1996). Positron Emission Tomography Neuroimaging in Dementia. In: E.Bigler (Ed), Handbook of Human Brain Function. Plenum Press: New York, pp. 185-222..
  36. Yamaoka, L.H., Welsh-Bohmer, K.A., Hulette, C.M. Gaskell Jr., P.C., Murray, M., Rimmler, J.L., Helms, B.R., Guerra, M., Roses, A.D., Schmechel, D.E., Pericak-Vance, M.A. Linkage of Frontotemporal dementia to Chromosome 17: Clinical and neuropathological characterization of phenotype. American Journal of Human Genetics. (accepted)..
  37. 1995.
  38. Breitner, J.C.S. & Welsh, K.A. (1995). An approach to diagnosis and management of memory loss and other cognitive syndromes of aging. Psychiatric Services: A Journal of the American Psychiatric Association , 46, 29-35..
  39. Breitner, J.C.S. & Welsh, K.A. (1995). Genes and recent developments in the epidemiology of Alzheimer's disease and related dementia. Epidemiology Reviews, 17, 39-47..
  40. Breitner, J.C.S., Welsh, K.A., Gau, B.A., McDonald WM, Steffens DC, Saunders AM, Magruder KM, Helms MJ, Blassman BL, Folstein MF, Brandt J, Robinette CD, Page WF. (1995). Alzheimer's disease in the National Academy of Sciences- National Research Council Registry of Aging Twin Veterans. III. Detection of Cases, longitudinal results, and observations on twin concordance. Archives of Neurology, 52, 763-771..
  41. Plassman, B.L., Breitner, J.C.S., Helms, M.J., Welsh, K.A., & Saunders, A.M. (1995) Confounding with genes may explain the inverse association of smoking and Alzheimer's disease. Lancet, 345, 387..
  42. Plassman, B.L., Saunders, A.M., Helms, M.J., Breitner JCS, & Welsh, K.A.,. (1995). Smoking, Alzheimer's disease, and confounding with genes. Author's reply. Lancet, 345, 1054 ..
  43. Plassman, B.L., Welsh, K.A., Helms, M., Brandt, J., Page, W.F., & Breitner, J.C.S. (1995) Intelligence and education as predictor of cognitive state in late life: A 50 year follow-up. Neurology, 45: 1446-1450..
  44. Tupler, L.A., Welsh, K.A., Asare-Aboagye, Y., Dawson, D.V. (1995). Reliability of the Rey-Osterrieth Complex Figure in use with memory impaired patients. Journal of Clinical and Experimental Neuropsychology, 17, 566-579..
  45. Welsh, K.A., Fillenbaum, G., Wilkinson, W., Heyman, A., Mohs, R.C., Stern, Y., & Harrell, L. (1995). Neuropsychological performance of black and white patients with Alzheimer's disease. Neurology, 45: 2207-2211..
  46. 1994.
  47. Breitner JCS, Gau B, Welsh KA, Plassman B, Helms M, Anthony J: Inverse association betrween anti-inflammatory agents and Alzheimer's disease: Initial results of a co-twin control study. Neurology 44: 227-232, 19994..
  48. Breitner JCS, Welsh KA, Robinette CD, Gau BA, Folstein MF, Brandt J: Alzheimer's disease in the National Academy of Sciences Registry of Aging Twin Veterans II. Longitudinal findings in a pilot series. Dementia 5: 99-105, 1994..
  49. Fillenbaum, G. G., Burchett, B.M., & Welsh, K.A. The 20-item word list as a measure of cognitive functioning in the Health and Retirement Survey: Norms and validity for White, Black, and Hispanic respondents. Health and Retirement Study Working Paper Series, Paper #94-005. Institute for Social Research at the University of Michigan & the National Institute of Aging..
  50. Norton M.C., Breitner, J.C.S., Welsh, K.A., & Wyse, B.W. (1994). Characteristics of nonresponders in a community survey of the elderly. Journal of the American Geriatrics Society, 42: 1252-1256..
  51. Reed T., Swan G., Carmeli D., Christian, J., Breitner J.C.S., Welsh, K.A. (1994). Lower cognitive performance in normal older adult male twins carrying the Apolipoprotein E e4 allele. Archives of Neurology, 51, 1189-1192..
  52. Welsh K.A., Ballard E., Nash F., Raiford K., & Harrell L. (1994). Issues affecting minority participation in studies of Alzheimer's disease. Alzheimer's Disease and Associated Disorders, 8 (Suppl 4), 38-48..
  53. Welsh K.A., Butters N., Mohs R.C., Beekly D., Edland S., Fillenbaum, G, & Heyman A..
  54. Welsh K.A., Hoffman J.M., Earl N.L., & Hansen, M. W. (1994) Neural correlates of dementia: Regional brain metabolism (FDG-PET) and the CERAD neuropsychological battery. Archives of Clinical Neuropsychology, 9, 395-409..
  55. Welsh KA, Butters N, Mohs RC, Beekly D, Edland S, Fillenbaum G, Heyman A: The consortius to establish a registry of Alzheimer's disease (CERAD) Part V: A normative study of the neuropsychological battery. Neurology 44: 609-614, 1994..
  56. Welsh KA, Hoffman JM, Earl NL, Hansen MW: Neural correlates of dementia: Regional brain metabolism (FDG-PET) and the CERAD neuropsychological battery. Archives of Clinical Neuropsychology 9: 395-409, 1994..
  57. 1993.
  58. Brandt J., Welsh K.A., Breitner J.C.S., Folstein, M.F., Helms, M, & Christian, J.C. (1993). Hereditary influences on cognitive functioning in older men: A study of 4,000 twin-pairs. Archives of Neurology, 50, 599-603..
  59. Breitner, J.C.S., Gatz, M., Bergem A.L.M., Christian J.C., Mortimer, J.A., McClearn, G.E., Heston L.L., Welsh, K.A., Anthony, J.C., Folstein, M.F., & Radebaugh, T.S. (1993). The use of Twin Cohorts for Research in Alzheimer's Disease: A consensus document sponsored by the NIA and Duke University Collaborative Twin Studies. Neurology, 43, 261-267..
  60. Welsh K.A., Breitner J.C.S., & Magruder-Habib, K.M. (1993). Detection of dementia in community volunteers using telephone screening of cognitive status. Neuropsychiatry, Neuropsychology, and Behavioral Neurology, 6, 103-110..
  61. Welsh K.A., Hoffman J.M., McDonald J.M., Earl N.L., & Breitner J.C.S. (1993). Concordant but different: Cognitive function, cerebral anatomy, and brain metabolism in monozygotic twins with Alzheimer's disease. Neuropsychology, 7, 158-171..