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Publications [#277289] of Redford B. Williams

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Journal Articles

  1. Roy, A; Berman, J; Williams, R; Kuhn, C; Gonzalez, B (2002). Higher levels of CSF homovanillic acid in recently abstinent cocaine-dependent patients. American Journal of Psychiatry, 159(6), 1053-1055. [doi]
    (last updated on 2019/04/19)

    Abstract:
    Objective: The authors examined an index of dopaminergic neurotransmission in recently abstinent cocaine-dependent patients. Method: CSF concentrations of the dopamine metabolite homovanillic acid (HVA) were determined in 30 recently abstinent cocaine-dependent patients and 69 healthy comparison subjects. Results: The cocaine-dependent patients had a significantly higher mean concentration of CSF HVA than did the healthy comparison group. Conclusions: Recently abstinent cocaine-dependent patients may show dysregulation of the central dopaminergic system.


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