Publications [#277392] of Redford B. Williams

Journal Articles

1. Williams, RB; Ng, LK; Lamprecht, F; Roth, K; Kopin, IJ (1973). 9 -Tetrahydrocannabinol: a hypotensive effect in rats.. Psychopharmacologia, 28(3), 269-274. [doi]
   (last updated on 2023/06/01)

   Abstract:
   The effects of δ9-tetrahydrocannabinol upon rat blood pressure were studied in control rats and in rats subjected to repeated immobilization stress over seven days. The immobilization stress was associated with a significant blood pressure increase in animals not receiving δ9-THC. δ9-THC resulted in a significant lowering of blood pressure in non-immobilized rats and blocked the appearance of hypertension in immobilized rats. These data support previous suggestions that THC compounds might be useful in an approach to the therapy of hypertension. © 1973 Springer-Verlag.