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Publications [#273466] of Richard S. Keefe

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Journal Articles

  1. Kraus, MS; Keefe, RSE; Krishnan, RKR (2009). Memory-prediction errors and their consequences in schizophrenia. Neuropsychology Review, 19(3), 336-352. [doi]
    (last updated on 2019/02/19)

    Abstract:
    Cognitive deficits play a central role in the onset of schizophrenia. Cognitive impairment precedes the onset of psychosis in at least a subgroup of patients, and accounts for considerable dysfunction. Yet cognitive deficits as currently measured are not significantly related to hallucinations and delusions. Part of this counterintuitive absence of a relationship may be caused by the lack of an organizing principle of cognitive impairment in schizophrenia research. We review literature suggesting that a system of memory-based prediction is central to human perception, thought and action, and forward the notion that many of the symptoms of schizophrenia are a result of a failure of this system. © 2009 Springer Science+Business Media, LLC.


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