Psychology and Neuroscience Faculty Database
Psychology and Neuroscience
Arts & Sciences
Duke University

 HOME > Arts & Sciences > pn > Faculty    Search Help Login pdf version printable version 

Publications [#273536] of Richard S. Keefe

search PubMed.

Journal Articles

  1. Keefe, RSE; Mohs, RC; Losonczy, MF; Davidson, MD; Silverman, JM; Horvath, TB; Davis, KL (1989). Premorbid sociosexual functioning and long-term outcome in schizophrenia. American Journal of Psychiatry, 146(2), 206-211.
    (last updated on 2019/04/22)

    Chronic schizophrenic patients with the most severe social deterioration have been shown to differ from other chronic schizophrenic patients with respect to measures of left-to-right ventricular asymmetry, negative symptoms, and response to haloperidol treatment. In the current study, the authors investigated the social antecedents of these characteristics of very poor outcome schizophrenia in 69 chronic schizophrenic patients. Poor premorbid sociosexual functioning was associated with more severe left-to-right ventricular asymmetry, greater severity of negative symptoms, fewer positive symptoms, and worse current social functioning. These data suggest that factors associated with severe social deterioration in the end stage of schizophrenia are also associated with premorbid sociosexual impairment.

Duke University * Arts & Sciences * Faculty * Staff * Grad * Postdocs * Reload * Login