| Publications [#52095] of Ruey-Kuang Cheng
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- Hakak, O.L. *Cheng, R.K., Williams, C.L. & Meck. W.H. (March 17, 2007).
Effects of sex and prenatal choline treatments on environmental and object exploration. (Poster presentation given at the 14th annual meeting of the International Conference on Comparative Cognition, Melbourne Beach, FL).
(last updated on 2007/04/10)
Abstract: Prenatal choline supplementation has been shown to enhance adult rats’ performance on cognitive tasks. Recent studies have associated prenatal choline supplementation with increased gamma oscillations in the adult hippocampus, which in turn are suggested as important for memory consolidation during sleep states. In this study, we explored whether prenatally choline supplemented rats of both sexes would spend more time interacting with novel objects, and subsequently engage in more REM sleep. Local field potentials were recorded in the dentate gyrus of 36 rats of both sexes and different prenatal choline backgrounds (i.e., deficient, sufficient, and supplemented) during both interaction with novel objects and subsequent sleep. Preliminary analysis indicated that environmental and object exploration did not correlate with prenatal choline treatments. A significant sex difference was observed, however, for these two behaviors, suggesting that female rats interacted more with the novel objects and environments than did males.
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