publications by Adam P. Wax.


Papers Published

  1. Graf, Robert N. and Wax, Adam, Nuclear morphology measurements using Fourier domain low coherence interferometry, Optics Express, vol. 13 no. 12 (2005), pp. 4693 - 4698 .
    (last updated on 2007/04/14)

    Abstract:
    We present a new common path configuration Fourier domain low coherence interferometry (fLCI) optical system and demonstrate its capabilities by presenting results which determine the size of cell nuclei in a monolayer of T84 epithelial cells. The optical system uses a white light source in a modified Michelson interferometer and a spectrograph for detection of the mixed signal and reference fields. Depth resolution is obtained from the Fourier transform of the measured spectrum which provides the axial spatial cross-correlation between the signal and reference fields. The spectral dependence of scattering by the samples is determined by windowing the spectrum to measure the scattering amplitude as a function of wavenumber. We present evidence that fLCI accurately measures the longitudinal profile of cell nuclei rather than the transverse profile. © 2005 Optical Society of America.

    Keywords:
    Coherent light;Interferometry;Morphology;Monolayers;Fourier transforms;Spectrographs;Optical correlation;Light scattering;