Mark W Dewhirst, Professor of Radiation Oncology and Biomedical Engineering  


Mark W Dewhirst
Contact Info:
Office Location:  201 Med Sci Res Building
Email Address:   send me a message
Web Page: http://www.radonc.duke.edu/department/academ/div/cancerbio/faculty/dewhirst.html

Education:

Ph.D., Colorado State University At Fort Collins, 1979
Specialties:

Medical Imaging
Representative Publications   (More Publications)

  1. KM Kennedy, MW Dewhirst, Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation., Future oncology (London, England), England, vol. 6 no. 1 (January, 2010), pp. 127-48  [abs].
  2. LW Jones, BL Viglianti, JA Tashjian, SM Kothadia, ST Keir, SJ Freedland, MQ Potter, E Jung Moon, T Schroeder, JE Herndon, MW Dewhirst, Effect of Aerobic Exercise on Tumor Physiology in an Animal Model of Human Breast Cancer., Journal of applied physiology (Bethesda, Md. : 1985) (December, 2009)  [abs].
  3. MW Dewhirst, Relationships between cycling hypoxia, HIF-1, angiogenesis and oxidative stress., Radiation research, United States, vol. 172 no. 6 (December, 2009), pp. 653-65  [abs].
  4. OI Craciunescu, PR Stauffer, BJ Soher, CR Wyatt, O Arabe, P Maccarini, SK Das, KS Cheng, TZ Wong, EL Jones, MW Dewhirst, Z Vujaskovic, JR MacFall, Accuracy of real time noninvasive temperature measurements using magnetic resonance thermal imaging in patients treated for high grade extremity soft tissue sarcomas., Medical physics, United States, vol. 36 no. 11 (November, 2009), pp. 4848-58  [abs].
  5. GM Palmer, RJ Boruta, BL Viglianti, L Lan, I Spasojevic, MW Dewhirst, Non-invasive monitoring of intra-tumor drug concentration and therapeutic response using optical spectroscopy., Journal of controlled release : official journal of the Controlled Release Society (November, 2009)  [abs].
  6. G Zhang, GM Palmer, MW Dewhirst, CL Fraser, A dual-emissive-materials design concept enables tumour hypoxia imaging., Nature materials, England, vol. 8 no. 9 (September, 2009), pp. 747-51  [abs].
  7. BL Viglianti, M Lora-Michiels, JM Poulson, L Lan, D Yu, L Sanders, O Craciunescu, Z Vujaskovic, DE Thrall, J Macfall, CH Charles, T Wong, MW Dewhirst, Dynamic contrast-enhanced magnetic resonance imaging as a predictor of clinical outcome in canine spontaneous soft tissue sarcomas treated with thermoradiotherapy., Clinical cancer research : an official journal of the American Association for Cancer Research, United States, vol. 15 no. 15 (August, 2009), pp. 4993-5001  [abs].
  8. GM Palmer, RJ Viola, T Schroeder, PS Yarmolenko, MW Dewhirst, N Ramanujam, Quantitative diffuse reflectance and fluorescence spectroscopy: tool to monitor tumor physiology in vivo., Journal of biomedical optics, United States, vol. 14 no. 2 (July, 2009), pp. 024010  [abs].
  9. ME Hardee, MW Dewhirst, N Agarwal, BS Sorg, Novel imaging provides new insights into mechanisms of oxygen transport in tumors., Current molecular medicine, Netherlands, vol. 9 no. 4 (May, 2009), pp. 435-41  [abs].
  10. AR Pries, AJ Cornelissen, AA Sloot, M Hinkeldey, MR Dreher, M Höpfner, MW Dewhirst, TW Secomb, Structural adaptation and heterogeneity of normal and tumor microvascular networks., PLoS computational biology, United States, vol. 5 no. 5 (May, 2009), pp. e1000394  [abs].
  11. MC Skala, A Fontanella, H Hendargo, MW Dewhirst, JA Izatt, Combined hyperspectral and spectral domain optical coherence tomography microscope for noninvasive hemodynamic imaging., Optics letters, United States, vol. 34 no. 3 (February, 2009), pp. 289-91  [abs].
  12. OI Craciunescu, KL Blackwell, EL Jones, JR Macfall, D Yu, Z Vujaskovic, TZ Wong, V Liotcheva, EL Rosen, LR Prosnitz, TV Samulski, MW Dewhirst, DCE-MRI parameters have potential to predict response of locally advanced breast cancer patients to neoadjuvant chemotherapy and hyperthermia: a pilot study., International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, England, vol. 25 no. 6 (2009), pp. 405-15  [abs].
  13. RJ Viola, JM Provenzale, F Li, CY Li, H Yuan, J Tashjian, MW Dewhirst, In vivo bioluminescence imaging monitoring of hypoxia-inducible factor 1alpha, a promoter that protects cells, in response to chemotherapy., AJR. American journal of roentgenology, United States, vol. 191 no. 6 (December, 2008), pp. 1779-84  [abs].
  14. P Sonveaux, F Végran, T Schroeder, MC Wergin, J Verrax, ZN Rabbani, CJ De Saedeleer, KM Kennedy, C Diepart, BF Jordan, MJ Kelley, B Gallez, ML Wahl, O Feron, MW Dewhirst, Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice., The Journal of clinical investigation, United States, vol. 118 no. 12 (December, 2008), pp. 3930-42  [abs].
  15. LI Cárdenas-Navia, D Mace, RA Richardson, DF Wilson, S Shan, MW Dewhirst, The pervasive presence of fluctuating oxygenation in tumors., Cancer research, United States, vol. 68 no. 14 (July, 2008), pp. 5812-9  [abs].
  16. MW Dewhirst, Y Cao, B Moeller, Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response., Nature reviews. Cancer, England, vol. 8 no. 6 (June, 2008), pp. 425-37  [abs].
  17. BS Sorg, ME Hardee, N Agarwal, BJ Moeller, MW Dewhirst, Spectral imaging facilitates visualization and measurements of unstable and abnormal microvascular oxygen transport in tumors., Journal of biomedical optics, United States, vol. 13 no. 1 (June, 2008), pp. 014026  [abs].
  18. AA Manzoor, T Schroeder, MW Dewhirst, One-stop-shop tumor imaging: buy hypoxia, get lactate free., The Journal of clinical investigation, United States, vol. 118 no. 5 (May, 2008), pp. 1616-9  [abs].
  19. G Vlahovic, AM Ponce, Z Rabbani, FK Salahuddin, L Zgonjanin, I Spasojevic, Z Vujaskovic, MW Dewhirst, Treatment with imatinib improves drug delivery and efficacy in NSCLC xenografts., British journal of cancer, England, vol. 97 no. 6 (September, 2007), pp. 735-40  [abs].
  20. MR Dreher, W Liu, CR Michelich, MW Dewhirst, A Chilkoti, Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors., Cancer research, United States, vol. 67 no. 9 (May, 2007), pp. 4418-24  [abs].
  21. F Li, P Sonveaux, ZN Rabbani, S Liu, B Yan, Q Huang, Z Vujaskovic, MW Dewhirst, CY Li, Regulation of HIF-1alpha stability through S-nitrosylation., Molecular cell, United States, vol. 26 no. 1 (April, 2007), pp. 63-74  [abs].
  22. Y Cao, P Sonveaux, S Liu, Y Zhao, J Mi, BM Clary, CY Li, CD Kontos, MW Dewhirst, Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth., Cancer research, United States, vol. 67 no. 8 (April, 2007), pp. 3835-44  [abs].
  23. MW Dewhirst, Intermittent hypoxia furthers the rationale for hypoxia-inducible factor-1 targeting., Cancer research, United States, vol. 67 no. 3 (February, 2007), pp. 854-5  [abs].
  24. AM Ponce, BL Viglianti, D Yu, PS Yarmolenko, CR Michelich, J Woo, MB Bally, MW Dewhirst, Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects., Journal of the National Cancer Institute, United States, vol. 99 no. 1 (January, 2007), pp. 53-63  [abs].
  25. MW Dewhirst, IC Navia, DM Brizel, C Willett, TW Secomb, Multiple etiologies of tumor hypoxia require multifaceted solutions., Clinical cancer research : an official journal of the American Association for Cancer Research, United States, vol. 13 no. 2 Pt 1 (January, 2007), pp. 375-7 .
  26. ME Hardee, Y Cao, P Fu, X Jiang, Y Zhao, ZN Rabbani, Z Vujaskovic, MW Dewhirst, MO Arcasoy, Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression., PloS one, United States, vol. 2 no. 6 (2007), pp. e549  [abs].
  27. M Lora-Michiels, D Yu, L Sanders, JM Poulson, C Azuma, B Case, Z Vujaskovic, DE Thrall, HC Charles, MW Dewhirst, Extracellular pH and P-31 magnetic resonance spectroscopic variables are related to outcome in canine soft tissue sarcomas treated with thermoradiotherapy., Clinical cancer research : an official journal of the American Association for Cancer Research, United States, vol. 12 no. 19 (October, 2006), pp. 5733-40  [abs].
  28. DE Thrall, SM Larue, AF Pruitt, B Case, MW Dewhirst, Changes in tumour oxygenation during fractionated hyperthermia and radiation therapy in spontaneous canine sarcomas., International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, England, vol. 22 no. 5 (August, 2006), pp. 365-73  [abs].
  29. KO Hicks, FB Pruijn, TW Secomb, MP Hay, R Hsu, JM Brown, WA Denny, MW Dewhirst, WR Wilson, Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugs., Journal of the National Cancer Institute, United States, vol. 98 no. 16 (August, 2006), pp. 1118-28  [abs].
  30. ML Hauck, SM LaRue, WP Petros, JM Poulson, D Yu, I Spasojevic, AF Pruitt, A Klein, B Case, DE Thrall, D Needham, MW Dewhirst, Phase I trial of doxorubicin-containing low temperature sensitive liposomes in spontaneous canine tumors., Clinical cancer research : an official journal of the American Association for Cancer Research, United States, vol. 12 no. 13 (July, 2006), pp. 4004-10  [abs].
  31. H Yuan, T Schroeder, JE Bowsher, LW Hedlund, T Wong, MW Dewhirst, Intertumoral differences in hypoxia selectivity of the PET imaging agent 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone)., Journal of nuclear medicine : official publication, Society of Nuclear Medicine, United States, vol. 47 no. 6 (June, 2006), pp. 989-98  [abs].
  32. MR Dreher, W Liu, CR Michelich, MW Dewhirst, F Yuan, A Chilkoti, Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers., Journal of the National Cancer Institute, United States, vol. 98 no. 5 (March, 2006), pp. 335-44  [abs].
  33. J Lanzen, RD Braun, B Klitzman, D Brizel, TW Secomb, MW Dewhirst, Direct demonstration of instabilities in oxygen concentrations within the extravascular compartment of an experimental tumor., Cancer research, United States, vol. 66 no. 4 (February, 2006), pp. 2219-23  [abs].
  34. HK Dressman, C Hans, A Bild, JA Olson, E Rosen, PK Marcom, VB Liotcheva, EL Jones, Z Vujaskovic, J Marks, MW Dewhirst, M West, JR Nevins, K Blackwell, Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy., Clinical cancer research : an official journal of the American Association for Cancer Research, United States, vol. 12 no. 3 Pt 1 (February, 2006), pp. 819-26  [abs].
  35. BS Sorg, BJ Moeller, O Donovan, Y Cao, MW Dewhirst, Hyperspectral imaging of hemoglobin saturation in tumor microvasculature and tumor hypoxia development., Journal of biomedical optics, United States, vol. 10 no. 4 (December, 2005), pp. 44004  [abs].
  36. SK Das, J Macfall, R McCauley, O Craciunescu, MW Dewhirst, TV Samulski, Improved magnetic resonance thermal imaging by combining proton resonance frequency shift (PRFS) and apparent diffusion coefficient (ADC) data., International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, England, vol. 21 no. 7 (November, 2005), pp. 657-67  [abs].
  37. BJ Moeller, MR Dreher, ZN Rabbani, T Schroeder, Y Cao, CY Li, MW Dewhirst, Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity., Cancer cell, United States, vol. 8 no. 2 (August, 2005), pp. 99-110  [abs].
  38. Y Cao, CY Li, BJ Moeller, D Yu, Y Zhao, MR Dreher, S Shan, MW Dewhirst, Observation of incipient tumor angiogenesis that is independent of hypoxia and hypoxia inducible factor-1 activation., Cancer research, United States, vol. 65 no. 13 (July, 2005), pp. 5498-505  [abs].
  39. DE Thrall, SM LaRue, D Yu, T Samulski, L Sanders, B Case, G Rosner, C Azuma, J Poulson, AF Pruitt, W Stanley, ML Hauck, L Williams, P Hess, MW Dewhirst, Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapy., Clinical cancer research : an official journal of the American Association for Cancer Research, United States, vol. 11 no. 14 (July, 2005), pp. 5206-14  [abs].
  40. EL Jones, JR Oleson, LR Prosnitz, TV Samulski, Z Vujaskovic, D Yu, LL Sanders, MW Dewhirst, Randomized trial of hyperthermia and radiation for superficial tumors., Journal of clinical oncology : official journal of the American Society of Clinical Oncology, United States, vol. 23 no. 13 (May, 2005), pp. 3079-85  [abs].
  41. MW Dewhirst, JM Poulson, D Yu, L Sanders, M Lora-Michiels, Z Vujaskovic, EL Jones, TV Samulski, BE Powers, DM Brizel, LR Prosnitz, HC Charles, Relation between pO2, 31P magnetic resonance spectroscopy parameters and treatment outcome in patients with high-grade soft tissue sarcomas treated with thermoradiotherapy., International journal of radiation oncology, biology, physics, United States, vol. 61 no. 2 (February, 2005), pp. 480-91  [abs].
  42. AC Lockhart, RD Braun, D Yu, JR Ross, MW Dewhirst, JS Humphrey, S Thompson, KM Williams, B Klitzman, F Yuan, JM Grichnik, AD Proia, DA Conway, HI Hurwitz, Reduction of wound angiogenesis in patients treated with BMS-275291, a broad spectrum matrix metalloproteinase inhibitor., Clinical cancer research : an official journal of the American Association for Cancer Research, United States, vol. 9 no. 2 (February, 2003), pp. 586-93  [abs].
  43. MW Dewhirst, Mechanisms underlying hypoxia development in tumors., Advances in experimental medicine and biology, United States, vol. 510 (2003), pp. 51-6 .
  44. RA Richardson, MW Dewhirst, The effect of nicotinamide & hyperoxic gases on blood glucose., Advances in experimental medicine and biology, United States, vol. 510 (2003), pp. 375-8 .
  45. EM Zeman, JR Dynlacht, BS Rosenstein, MW Dewhirst, ASTRO Joint Working Group on Radiobiology Teaching, Toward a national consensus: teaching radiobiology to radiation oncology residents., International journal of radiation oncology, biology, physics, United States, vol. 54 no. 3 (November, 2002), pp. 861-72  [abs].
  46. Z Vujaskovic, I Batinic-Haberle, ZN Rabbani, QF Feng, SK Kang, I Spasojevic, TV Samulski, I Fridovich, MW Dewhirst, MS Anscher, A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury., Free radical biology & medicine, United States, vol. 33 no. 6 (September, 2002), pp. 857-63  [abs].
  47. CW Wong, C Song, MM Grimes, W Fu, MW Dewhirst, RJ Muschel, AB Al-Mehdi, Intravascular location of breast cancer cells after spontaneous metastasis to the lung., The American journal of pathology, United States, vol. 161 no. 3 (September, 2002), pp. 749-53  [abs].
  48. BD Kavanagh, TW Secomb, R Hsu, PS Lin, J Venitz, MW Dewhirst, A theoretical model for the effects of reduced hemoglobin-oxygen affinity on tumor oxygenation., International journal of radiation oncology, biology, physics, United States, vol. 53 no. 1 (May, 2002), pp. 172-9  [abs].
  49. JR Dynlacht, MW Dewhirst, EJ Hall, BS Rosenstein, EM Zeman, Toward a consensus on radiobiology teaching to radiation oncology residents., Radiation research, United States, vol. 157 no. 5 (May, 2002), pp. 599-606  [abs].
  50. LP Hale, RD Braun, WM Gwinn, PK Greer, MW Dewhirst, Hypoxia in the thymus: role of oxygen tension in thymocyte survival., American journal of physiology. Heart and circulatory physiology, United States, vol. 282 no. 4 (April, 2002), pp. H1467-77  [abs].
  51. D Needham, MW Dewhirst, The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors., Advanced drug delivery reviews, Netherlands, vol. 53 no. 3 (December, 2001), pp. 285-305  [abs].
  52. BW Pogue, RD Braun, JL Lanzen, C Erickson, MW Dewhirst, Analysis of the heterogeneity of pO2 dynamics during photodynamic therapy with verteporfin., Photochemistry and photobiology, United States, vol. 74 no. 5 (November, 2001), pp. 700-6  [abs].
  53. F Lohr, Q Huang, K Hu, MW Dewhirst, CY Li, Systemic vector leakage and transgene expression by intratumorally injected recombinant adenovirus vectors., Clinical cancer research : an official journal of the American Association for Cancer Research, United States, vol. 7 no. 11 (November, 2001), pp. 3625-8  [abs].
  54. S Walenta, S Snyder, ZA Haroon, RD Braun, K Amin, D Brizel, W Mueller-Klieser, B Chance, MW Dewhirst, Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model., International journal of radiation oncology, biology, physics, United States, vol. 51 no. 3 (November, 2001), pp. 840-8  [abs].
  55. SN Ettinger, CC Poellmann, NA Wisniewski, AA Gaskin, JS Shoemaker, JM Poulson, MW Dewhirst, B Klitzman, Urea as a recovery marker for quantitative assessment of tumor interstitial solutes with microdialysis., Cancer research, United States, vol. 61 no. 21 (November, 2001), pp. 7964-70  [abs].
  56. DM Brizel, T Schroeder, RL Scher, S Walenta, RW Clough, MW Dewhirst, W Mueller-Klieser, Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer., International journal of radiation oncology, biology, physics, United States, vol. 51 no. 2 (October, 2001), pp. 349-53  [abs].
  57. SA Snyder, JL Lanzen, RD Braun, G Rosner, TW Secomb, J Biaglow, DM Brizel, MW Dewhirst, Simultaneous administration of glucose and hyperoxic gas achieves greater improvement in tumor oxygenation than hyperoxic gas alone., International journal of radiation oncology, biology, physics, United States, vol. 51 no. 2 (October, 2001), pp. 494-506  [abs].
  58. GM Tozer, VE Prise, J Wilson, M Cemazar, S Shan, MW Dewhirst, PR Barber, B Vojnovic, DJ Chaplin, Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability., Cancer research, United States, vol. 61 no. 17 (September, 2001), pp. 6413-22  [abs].
  59. A Lal, H Peters, B St Croix, ZA Haroon, MW Dewhirst, RL Strausberg, JH Kaanders, AJ van der Kogel, GJ Riggins, Transcriptional response to hypoxia in human tumors., Journal of the National Cancer Institute, United States, vol. 93 no. 17 (September, 2001), pp. 1337-43  [abs].
  60. S Shan, AC Lockhart, WY Saito, AM Knapp, KR Laderoute, MW Dewhirst, The novel tubulin-binding drug BTO-956 inhibits R3230AC mammary carcinoma growth and angiogenesis in Fischer 344 rats., Clinical cancer research : an official journal of the American Association for Cancer Research, United States, vol. 7 no. 8 (August, 2001), pp. 2590-6  [abs].
  61. DE Meyer, BC Shin, GA Kong, MW Dewhirst, A Chilkoti, Drug targeting using thermally responsive polymers and local hyperthermia., Journal of controlled release : official journal of the Controlled Release Society, Netherlands, vol. 74 no. 1-3 (July, 2001), pp. 213-24  [abs].
  62. Z Vujaskovic, MS Anscher, QF Feng, ZN Rabbani, K Amin, TS Samulski, MW Dewhirst, ZA Haroon, Radiation-induced hypoxia may perpetuate late normal tissue injury., International journal of radiation oncology, biology, physics, United States, vol. 50 no. 4 (July, 2001), pp. 851-5  [abs].
  63. RD Braun, JL Lanzen, SA Snyder, MW Dewhirst, Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents., American journal of physiology. Heart and circulatory physiology, United States, vol. 280 no. 6 (June, 2001), pp. H2533-44  [abs].
  64. RD Braun, JL Lanzen, JA Turnage, G Rosner, MW Dewhirst, Effects of the interaction between carbogen and nicotinamide on R3230 Ac tumor blood flow in Fischer 344 rats., Radiation research, United States, vol. 155 no. 5 (May, 2001), pp. 724-33  [abs].
  65. M Neeman, H Dafni, O Bukhari, RD Braun, MW Dewhirst, In vivo BOLD contrast MRI mapping of subcutaneous vascular function and maturation: validation by intravital microscopy., Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, United States, vol. 45 no. 5 (May, 2001), pp. 887-98  [abs].
  66. G Kong, RD Braun, MW Dewhirst, Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature., Cancer research, United States, vol. 61 no. 7 (April, 2001), pp. 3027-32  [abs].
  67. CE Connor, JD Norris, G Broadwater, TM Willson, MM Gottardis, MW Dewhirst, DP McDonnell, Circumventing tamoxifen resistance in breast cancers using antiestrogens that induce unique conformational changes in the estrogen receptor., Cancer research, United States, vol. 61 no. 7 (April, 2001), pp. 2917-22  [abs].
  68. F Lohr, DY Lo, DA Zaharoff, K Hu, X Zhang, Y Li, Y Zhao, MW Dewhirst, F Yuan, CY Li, Effective tumor therapy with plasmid-encoded cytokines combined with in vivo electroporation., Cancer research, United States, vol. 61 no. 8 (April, 2001), pp. 3281-4  [abs].
  69. DE Meyer, GA Kong, MW Dewhirst, MR Zalutsky, A Chilkoti, Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia., Cancer research, United States, vol. 61 no. 4 (February, 2001), pp. 1548-54  [abs].
  70. M Neeman, JM Provenzale, MW Dewhirst, Magnetic resonance imaging applications in the evaluation of tumor angiogenesis., Seminars in radiation oncology, UNITED STATES, vol. 11 no. 1 (January, 2001), pp. 70-82  [abs].
  71. CY Li, JB Little, K Hu, W Zhang, L Zhang, MW Dewhirst, Q Huang, Persistent genetic instability in cancer cells induced by non-DNA-damaging stress exposures., Cancer research, United States, vol. 61 no. 2 (January, 2001), pp. 428-32  [abs].
  72. MW Dewhirst, H Kimura, SW Rehmus, RD Braun, D Papahadjopoulos, K Hong, TW Secomb, Microvascular studies on the origins of perfusion-limited hypoxia., The British journal of cancer. Supplement, ENGLAND, vol. 27 (July, 1996), pp. S247-51  [abs].
  73. DM Brizel, SP Scully, JM Harrelson, LJ Layfield, JM Bean, LR Prosnitz, MW Dewhirst, Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma., Cancer research, UNITED STATES, vol. 56 no. 5 (March, 1996), pp. 941-3  [abs].
  74. H Kimura, NZ Wu, R Dodge, DP Spencer, BM Klitzman, TM McIntyre, MW Dewhirst, Inhibition of radiation-induced up-regulation of leukocyte adhesion to endothelial cells with the platelet-activating factor inhibitor, BN52021., International journal of radiation oncology, biology, physics, UNITED STATES, vol. 33 no. 3 (October, 1995), pp. 627-33  [abs].
  75. HD Sostman, DM Prescott, MW Dewhirst, RK Dodge, DE Thrall, RL Page, JA Tucker, JM Harrelson, G Reece, KA Leopold, MR imaging and spectroscopy for prognostic evaluation in soft-tissue sarcomas., Radiology, UNITED STATES, vol. 190 no. 1 (January, 1994), pp. 269-75  [abs].
  76. PD Maguire, TV Samulski, LR Prosnitz, EL Jones, GL Rosner, B Powers, LW Layfield, DM Brizel, SP Scully, JM Harrelson, MW Dewhirst, A phase II trial testing the thermal dose parameter CEM43 degrees T90 as a predictor of response in soft tissue sarcomas treated with pre-operative thermoradiotherapy., International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, England, vol. 17 no. 4 , pp. 283-90  [abs].
  77. K Vishwanath, D Klein, K Chang, T Schroeder, MW Dewhirst, N Ramanujam, Quantitative optical spectroscopy can identify long-term local tumor control in irradiated murine head and neck xenografts., Journal of biomedical optics, United States, vol. 14 no. 5 , pp. 054051  [abs].
  78. ZA Haroon, K Amin, W Saito, W Wilson, CS Greenberg, MW Dewhirst, SU5416 delays wound healing through inhibition of TGF-beta 1 activation., Cancer biology & therapy, United States, vol. 1 no. 2 , pp. 121-6  [abs].