Biophotonics is concerned with the application of cutting-edge optoelectronic technologies to problems in the biomedical sciences. My research centers on the application of optical technologies for non-invasive, high-resolution imaging and sensing in living biological tissues. The technologies we use in my laboratory include acousto-optic and integrated-optic devices, femtosecond lasers, and ultrabroadband fiber optic telecommunications equipment. The applications of the systems we build include noninvasive medical diagnostics, in-vivo tomographic microscopes, and high-throughput three-dimensional small animal imaging systems for genomics studies. Our work involves multiple collaborations with engineers, biologists, and physicians at Duke and elsewhere.

Contact Info:

Office Location:	2573 CIEMAS
Office Phone:	+1 919 660 5128
Email Address:
Web Page:	http://www.fitzpatrick.duke.edu/biophotonics

Teaching (Fall 2008):

• BME 171.01, SIGNALS AND SYSTEMS

  Teer 115, TuTh 11:40 AM-12:55 PM

Education:

PhD, Massachusetts Institute of Technology, 1991

SM, Massachusetts Institute of Technology, 1988

SB, Massachusetts Institute of Technology, 1986

Specialties:

Medical Imaging
Photonics
Medical Diagnostics

Research Interests:

Professor Izatt's research interests are in the area of biophotonics and include coherence-based biomedical imaging and microscopy, novel technologies for ophthalmic imaging, and nanoscale studies of cellular morphology and dynamics.

Areas of Interest:

Optical coherence tomography and microscopy
Ophthalmic imaging technology
Field-based optical microscopy at the nanoscale
Laser-tissue interactions
Optical and ultrasonic signal processing
Novel methods for high-resolution minimally invasive medical imaging and tissue characterization

Awards, Honors, and Distinctions

Fellow, American Institute for Medical and Biological Engineering, 2007
Fellow, Society of Photo-Instrumentation Engineers (SPIE), 2008
NSF Early CAREER Award, National Science Foundation, 1996-2000
Fellow, American Society for Laser Medicine and Surgery, 1995

Recent Publications   (More Publications)

1. Ellerbee, Audrey K. and Izatt, Joseph A., Phase retrieval in low-coherence interferometric microscopy, Optics Letters, vol. 32 no. 4 (2007), pp. 388 - 390 [OL.32.000388]  [abs].
2. Applegate, B.E. and Izatt, J.A., Molecular imaging of endogenous and exogenous chromophores using ground state recovery pump-probe optical coherence tomography, Opt. Express (USA), vol. 14 no. 20 (2006)  [abs].
3. Bower, Bradley A. and Zhao, Mingtao and Izatt, Joseph A., Investigation of retinal vessel autoregulation using real-time spectral domain doppler optical coherence tomography, Proceedings of SPIE - The International Society for Optical Engineering, vol. 6079 (2006), pp. 60790 - [12.649192]  [abs].
4. Zawadzki, Robert J. and Fuller, Alfred R. and Zhao, Mingtao and Wiley, David F. and Choi, Stacey S. and Bower, Bradley A. and Hamann, Bernd and Izatt, Joseph A. and Werner, John S., 3D OCT imaging in clinical settings: Toward quantitative measurements of retinal structures, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 6138 (2006), pp. 613803 - [12.647567]  [abs].
5. Applegate, Brian E. and Izatt, Joseph A., Transient absorption and lifetime imaging with ground state recovery pump-probe optical coherence tomography, Proceedings of SPIE - The International Society for Optical Engineering, vol. 6079 (2006), pp. 607902 - [12.649111]  [abs].