publications by Joseph A. Izatt.

Papers Published

  1. van Leeuwen, T.G. and Kulkarni, M.D. and Yazdanfar, S. and Rollins, A.M. and Izatt, J.A., High-flow-velocity and shear-rate imaging by use of color Doppler optical coherence tomography, Opt. Lett. (USA), vol. 24 no. 22 (1999), pp. 1584 - 6 .
    (last updated on 2007/04/13)

    Color Doppler optical coherence tomography (CDOCT) is capable of precise velocity mapping in turbid media. Previous CDOCT systems based on the short-time Fourier transform have been limited to maximum flow velocities of the order of tens of millimeters per second. We describe a technique, based on interference signal demodulation at multiple frequencies, to extend the physiological relevance of CDOCT by increasing the dynamic range of measurable velocities to hundreds of millimeters per second. The physiologically important parameter of shear rate is also derived from CDOCT measurements. The measured flow-velocity profiles and shear-rate distributions correlate very well with theoretical predictions. The multiple demodulation technique, therefore, may be useful to monitor blood flow in vivo and to identify regions with high and low shear rates

    blood flow measurement;Doppler measurement;light coherence;optical tomography;velocity measurement;